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Funding Opportunity Alerts

Funding Opportunity Alerts The National Center for Health and the Aging (NCHATA) continually researches and disseminates funding opportunities via listserv, monthly newsletters, and other publications.

If you become aware of grant opportunities or other funding opportunities at your community, state and/or regional level please send the notice to info@healthandtheaging.org for review.

 

Service Area Competition Application Deadlines

The Service Area Competition Grant is open to all primary health center programs, please see announcement for more information. For technical assistance with changes to the application, please see the Service Area Competition Technical Assistance Manual.

SAC Table Dates JPEG4

Service Area Competition

Health centers improve the health of the Nation’s underserved communities and vulnerable populations by ensuring access to comprehensive, culturally competent, quality primary health care services. This Funding Opportunity Announcement (FOA) solicits applications for the Health Center Program’s Service Area Competition (SAC). The FOA details the SAC eligibility requirements, review criteria, and awarding factors for organizations seeking a grant for operational support for an announced service area under the Health Center Program, including Community Health Center (CHC, section 330(e)), Migrant Health Center (MHC, section 330(g)), Health Care for the Homeless (HCH, section 330(h)), and/or Public Housing Primary Care (PHPC, section 330(i)). For the purposes of this document, the term “health center” refers to the diverse types of health centers (i.e., CHC, MHC, HCH, and/or PHPC) supported under section 330 of the PHS Act, as amended.

Full Announcement


Current Funding Opportunity Alerts:


AHRQ Grants Policy and Guidance

OMB Circular A-110 provides access to certain research data developed with Federal support through the Freedom of Information Act (FOIA), 5 U.S.C. 552, in certain circumstances. Data that are (1) first produced in a project that is supported in whole or in part with Federal funds and (2) cited publicly and officially by a Federal agency in support of an action that has the force and effect of law (i.e., a regulation or administrative order) may be accessed through FOIA. If no Federal action is taken having the force and effect of law in reliance upon an AHRQ-supported research project, the underlying data are not subject to this disclosure requirement. Furthermore, even if a Federal regulatory action is taken in reliance on AHRQ-supported research data, disclosure of such data is limited in accordance with the AHRQ confidentiality statute, 42 USC 299c-3(c). NIH has provided general related guidance at http://grants.nih.gov/archive/grants/policy/a110/a110_guidance_dec1999.htm which does not include discussion of the exception applicable to confidential identifiable data collected under AHRQ's authorities.

Should applicants wish to place data collected under this FOA in a public archive, which can provide protections for the data (e.g., as required by confidentiality provisions of the statute applicable to AHRQ-supported projects, 42 USC 299c-3(c)) and manage the distribution of non-identifiable data for an indefinite period of time, they may. The application should include a description of any archiving plan in the study design and include information about this in the budget justification section of the application. In addition, applicants should consider how to structure informed consent statements or other human subject protection procedures to permit or restrict disclosures of identifiable data, as warranted.

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Multidisciplinary Studies of HIV/AIDS and Aging

Deadline: April 9, 2014; August 7, 2014; December 9, 2014; April 7, 2015

This FOA invites applications proposing to study HIV infection, HIV-associated conditions, HIV treatment, and/or biobehavioral or social factors associated with HIV/AIDS in the context of aging and/or in older adults. Research approaches of interest include clinical translational, observational, and intervention studies in domestic and international settings.

Full Announcement


Understanding and Promoting Health Literacy

Deadline: Please see announcement

The ultimate goal of this program announcement is to encourage empirical research on health literacy concepts, theory and interventions as these relate to the U.S. Department of Health and Human Services’ public health priorities that are outlined in its Healthy People initiative. Health literacy is defined as the degree to which individuals have the capacity to obtain, process, and understand basic health information and services needed to make appropriate health decisions.

Full Announcement


Behavioral and Social Science Research on Understanding and Reducing Health Disparities

Deadline: Please see announcement

The purpose of this program announcement is to encourage behavioral and social science research on the causes and solutions to health and disabilities disparities in the U. S. population. Health disparities between, on the one hand, racial/ethnic populations, lower socioeconomic classes, and rural residents and, on the other hand, the overall U.S. population are major public health concerns. Emphasis is placed on research in and among three broad areas of action: 1) public policy, 2) health care, and 3) disease/disability prevention. Particular attention is given to reducing “health gaps” among groups. Proposals that utilize an interdisciplinary approach, investigate multiple levels of analysis, incorporate a life-course perspective, and/or employ innovative methods such as system science or community-based participatory research are particularly encouraged.

Full Announcement


2014


Clinical Studies of Safety and Effectiveness of Orphan Products Research Project Grant (R01)

Deadline: October 16, 2014

The goal of FDA's OPD grant program is to support the clinical development of products for use in rare diseases or conditions where no current therapy exists or where the product being developed will be superior to the existing therapy. FDA provides grants for clinical studies on safety and/or effectiveness that will either result in, or substantially contribute to, market approval of these products. Applicants must include in the application's Background and Significance section documentation to support the assertion that the orphan disease or condition to be studied is a “rare disease or condition” and an explanation of how the proposed study will either help support product approval or provide essential data needed for product development.

Full Announcement


Academic-Community Partnership Conference Series

Deadline: October 17, 2014

The purpose of this grant opportunity is to bring together academic institutions/organizations and community organizations to identify opportunities for addressing health disparitiesthrough the use of Community-Based Participatory Research (CBPR). The objectives of meetings conducted as part of this award will be to: (1) establish and/or enhance academic-community partnerships; (2) identify community-driven research priorities, and (3) develop long-term collaborative CBPR research agendas.

Full Announcement


Minor Use Minor Species Development Drugs

Deadline:  December 5, 2014

Grants will be awarded up to $75,000 or up to $125,000 in total (direct plus indirect) costs per year for up to three (3) years. Please note the dollar limitation will apply to total costs, not direct costs. Applications for the smaller grants ($75,000) may be for any safety or effectiveness study supportive of new animal drug approval or conditional approval of the designated product for a designated intended use. Study proposals for the larger grants ($125,000) must be for studies that are of necessity of unusual complexity, duration, or size. FDA grants policies as described in the HHS Grants Policy Statement http://www.hhs.gov/grantsnet/adminis/gpd/index.htm will apply to the applications submitted and awards made in response to this FOA.Facilities and Administrative (F&A) costs requested by consortium participants are not included in the direct cost limitation. See NOT-OD-05-004.

Full Announcement


Mental Health Research Dissertation Grant to Increase Diversity (R36)

Deadline: December 22, 2014

The purpose of this Funding Opportunity Announcement (FOA), issued by the National Institute of Mental Health (NIMH), is to increase the diversity of the mental health research workforce by providing dissertation awards in all areas of research within the strategic priorities of the NIMH to individuals from diverse backgrounds underrepresented in mental health research to support the completion of the doctoral research project.

Full Announcement


2015


Cancer Education Grants Program

Deadline: January 7, 2015

The purpose of this Funding Opportunity Announcement is to support innovative educational efforts that would help to reduce cancer incidence, morbidity, and mortality, and that would improve the quality of life of cancer patients.

Full Announcement


Development of Mathematical Cognition and Reasoning and the Prevention of Math Learning Disabilities

Deadline: January 7, 2015

This Funding Opportunity Announcement (FOA) is intended to stimulate innovative, multidisciplinary research on the cognitive, neuroplasticity, genetic and environmental factors involved in math learning and learning disabilities. This research will advance our knowledge of the factors that contribute to the development, advancement, and impairment of mathematical cognition, including the ability to apprehend and reason about magnitude, number, temporal and spatial relationships, and concomitantly provide the evidence base to inform the design of effective (i.e., efficacious in "real world" contexts) interventions for the remediation and/or prevention of mathematical learning disabilities (MLD).

Full Announcement


NIMH Research Education Mentoring Programs for HIV/AIDS Researchers (R25)

Deadline: January 7, 2015

This Funding Opportunity Announcement (FOA) issued by the National Institute of Mental Health encourages Research Education Grant (R25) applications from Institutions/Organizations that propose to develop, implement, and evaluate creative and innovative research education mentoring programs that will facilitate the development of a cadre of investigators in requisite scientific research areas to advance the mental health-related objectives of the Office of AIDS Research (OAR) Annual Strategic Plan and program priorities of the NIMH Division of AIDS Research (DAR).

Full Announcement


Development of Mathematical Cognition and Reasoning and the Prevention of Math Learning Disabilities

Deadline: January 7, 2015

This Funding Opportunity Announcement (FOA) is intended to stimulate innovative, multidisciplinary research on the cognitive, neuroplasticity, genetic and environmental factors involved in math learning and learning disabilities. This research will advance our knowledge of the factors that contribute to the development, advancement, and impairment of mathematical cognition, including the ability to apprehend and reason about magnitude, number, temporal and spatial relationships, and concomitantly provide the evidence base to inform the design of effective (i.e., efficacious in "real world" contexts) interventions for the remediation and/or prevention of mathematical learning disabilities (MLD).

Full Announcement


Development of Mathematical Cognition and Reasoning and the Prevention of Math Learning Disabilities

Deadline: January 7, 2015

This Funding Opportunity Announcement (FOA) is intended to stimulate innovative, multidisciplinary research on the cognitive, neuroplasticity, genetic and environmental factors involved in math learning and learning disabilities. This research will advance our knowledge of the factors that contribute to the development, advancement, and impairment of mathematical cognition, including the ability to apprehend and reason about magnitude, number, temporal and spatial relationships, and concomitantly provide the evidence base to inform the design of effective (i.e., efficacious in "real world" contexts) interventions for the remediation and/or prevention of mathematical learning disabilities (MLD).

Full Announcement


Functional Glycomics in HIV Vaccine Design (R01)

Deadline: January 7, 2015

Glycans play key roles in the transmission, antigenicity, and immunogenicity of the HIV-1 envelope protein. Glycans also modulate the immune response, playing an essential role in both innate and adaptive immunity. The purpose of this Funding Opportunity Announcement (FOA) is to stimulate and foster multi-disciplinary investigator- initiated collaborative research to 1) investigate structural and conformational features of glycosylation that may lead to novel HIV vaccine design approaches, and 2) to elucidate the impact of differential glycosylation on the quality of the immune response to HIV. Ultimately, the discovery of a safe, effective, prophylactic vaccine that provides long-term protection from HIV infection may depend on novel approaches that incorporate new knowledge of the key role glycans play in the elicitation and maturation of broadly neutralizing antibodies and effector immune responses.

Full Announcement


Center of Excellence for Research on CAM (P01)

Deadline:  January 7, 2015

This funding opportunity announcement (FOA) encourages the submission of applications that propose to conduct research that is of high-priority to NCCAM that requires synergistic collaboration between outstanding scientists and the synthesis of multiple research approaches by multi-disciplinary research teams. The Center of Excellence for Research on CAM (CERC) program is designed to support research in which the funding of three or four synergistic, highly meritorious projects as a group offers significant scientific advantages over support of the same projects as individual research grants. Each CERC must consist of, throughout the duration of the award, a minimum of three research projects, focused on basic, mechanistic, and/or translational research questions relevant to the research priorities described in the current NCCAM Strategic Plan.

Full Announcement 


Tobacco Control Regulatory Research – R21

Deadline: January 16, 2015

The purpose of this Funding Opportunity Announcement (FOA) is to encourage biomedical, behavioral, and social science research that will inform the development and evaluation of regulations on tobacco product manufacturing, distribution, and marketing. Research projects must address the research priorities related to the regulatory authority of the Food and Drug Administration (FDA) Center for Tobacco Products (CTP) as mandated by the Family Smoking Prevention and Tobacco Control Act (FSPTCA), Public Law 111-31. The awards under this FOA will be administered by NIH using designated funds from the FDA CTP for tobacco regulatory science. Research results from this FOA are expected to generate findings and data that are directly relevant to inform the FDA's regulation of the manufacture, distribution, and marketing of tobacco products to protect public health.

Full Announcement


Interdisciplinary Complementary and Integrative Health Clinical Research Training Award (T90/R90)

Deadline: January 28, 2015

The National Center for Complementary and Alternative Medicine (NCCAM) is establishing this clinical research training program aimed at improving the capacity of the integrative health field to carry out rigorous research. This Funding Opportunity Announcement (FOA) will fund coherent and unified partnerships between institutions with research intensive environments (e.g., T32 and CTSA institutions) and institutions with curricula focused on clinical training of practitioners in complementary modalities and disciplines that also have faculty with a substantial interest in rigorous clinical research. The program will support mentored research training and hands-on experiences in clinical research, as well as trainee-focused developmental efforts including didactic activities in clinical research methodology, integrative health, and trainee-initiated pilot clinical research projects within NCCAM's research priority areas. The funded institutional programs are expected to generate a cadre of research clinicians who are able to participate fully in multi-disciplinary teams engaged in complementary and integrative health research.

Full Announcement


Countermeasures Against Chemical Threats (CounterACT) Exploratory/Developmental Projects in Translational Research (R21)

Deadline: January 30, 2015

This Funding Opportunity Announcement (FOA) encourages applications for exploratory/developmental translational research on therapeutics for reducing mortality and morbidity caused by acute exposures to chemical threat agents. Chemical threats include chemical warfare nerve agents such as sarin and VX, toxic industrial chemicals such as cyanide and phosgene, and toxic agricultural chemicals such as parathion and sodium fluoroacetate. Projects supported by this FOA are expected to generate preliminary preclinical, screening and efficacy data that would enable the development of competitive applications for more extensive support from the NIH CounterACT program (see www.ninds.nih.gov/counteract for a description) and other related translational research programs.

Full Announcement


NIDCD Research On Hearing Health Care (R21/R33)

Deadline:  February 24, 2015

This funding opportunity announcement (FOA) invites Exploratory/Developmental Phased Innovation (R21/R33) grant applications to support research and/or infrastructure needs leading to more accessible and affordable hearing health care (HHC). The proposed research aims should lead to the delivery of better healthcare access and outcomes and be directed to solutions that are effective, affordable and deliverable to those who need them. Outcomes and health services research are also responsive to this FOA. This FOA provides support for up to two years (R21 phase) for preliminary/development studies, followed by possible transition of up to four years of expanded research and development support (R33 phase). The total project period for an application submitted in response to this FOA may not exceed five years. This FOA requires measurable R21 milestones.

Full Announcement 


Translational Research to Improve Obesity and Diabetes Outcomes

Deadline: March 2, 2015

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) encourages NIH Research Demonstration and Dissemination Project grant (R18) applications from institutions/ organizations to test practical, sustainable, acceptable, and cost efficient adaptations of efficacious strategies or approaches prevent and treat diabetes and/or obesity. Research must target the prevention or reversal of obesity, prevention of type 2 diabetes, improved care of type 1 and type 2 diabetes, or the prevention or delay of the complications of these conditions. The approaches tested should have the potential to be widely disseminated to clinical practice, individuals and communities at risk.

Full Announcement


International Research Scientist Development Award (IRSDA) (K01)

Deadline: March 4, 2015

The purpose of the Fogarty International Center (FIC) International Research Scientist Development Award (IRSDA) is to provide support and protected time (three to five years) to advanced postdoctoral (at least two years beyond conferral of doctoral degree) U.S. research scientists for an intensive, mentored research career development experience in a low- or middle-income country (LMIC) as defined by the World Bank (http://data.worldbank.org/about/country-classifications/country-and-lending-groups; low-income, lower-middle-income, and upper-middle-income countries are included) leading to an independent research career focused on global health. FIC invites K01 applications from biomedical, epidemiological, clinical, biostatistical, social and behavioral scientists in the formative stages of their research careers.

Full Announcement


New Directions in Hematology Research (SHINE-II) (R01)

Deadline: March 7, 2015

This research Funding Opportunity Announcement (FOA), New Directions in Hematology Research (SHINE-II), is intended to promote innovative research initiatives that explore high impact, new directions of inquiry relevant to the hematology research mission of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). This new Funding Opportunity builds upon the objectives of an on-going program defined by PAS-10-046: Stimulating Hematology Investigation: New Endeavors (or SHINE). With the SHINE-II program, NIDDK invites investigator-initiated grant applications for pre-clinical, proof of principle research projects that are tightly focused and directed at validating novel concepts and approaches that promise to open up new pathways for discovery. Research applications submitted under this FOA should be more limited in scope (a single central aim) and duration (1-3 years) than typical R01 grant applications.

Full Announcement


System-level Workforce Capacity Building for Integrating HIV Primary Care in Community Health Care Settings – Demonstration Sites Deadline: March 10, 2014 This announcement solicits applications for a new Ryan White HIV/AIDS Program Special Projects of National Significance (SPNS) multi-site initiative entitled System-level Workforce Capacity Building for Integrating HIV Primary Care in Community Health Care Settings ¿ Demonstration Sites. .Eligible demonstration site applicants must be public or private non-profit organizations that receive funding under Ryan White HIV/AIDS Treatment Extension Act of 2009. Full Announcement http://www.grants.gov/web/grants/view-opportunity.html?oppId=249905


System-level Workforce Capacity Building for Integrating HIV Primary Care in Community Healthcare Settings – Evaluation and Technical Assistance Center Cooperative Agreement Deadline: March 10, 2014This announcement solicits applications for fiscal year (FY) 2014 to support a single organization that will serve as an Evaluation and Technical Assistance Center (ETAC) for a new Ryan White HIV/AIDS Program Special Projects of National Significance (SPNS) multi-site initiative entitled System-level Workforce Capacity Building for Integrating HIV Primary Care in Community Healthcare Settings. Full Announcement



Integrated Preclinical/Clinical AIDS Vaccine Development Program (IPCAVD) (U19)

Deadline: March 13, 2015

The goal of the IPCAVD Funding Opportunity Announcement (FOA) issued by the National Institute of Allergy and Infectious Diseases (NIAID) is to facilitate the translation of sufficiently advanced, innovative and promising vaccine candidates into early clinical testing. The IPCAVD program is designed to enable a multi-disciplinary team of investigators to complete all steps necessary from down-selection of a vaccine candidate through CGMP manufacture/testing/product release and into clinical trials. A preclinical research application alone is not sufficient for this announcement. Awards will provide the critical resources to allow the advancement of vaccine concepts to clinical trials within the first 5 years of the award. The reduced support for two additional years will support ongoing stability studies, updating regulatory submissions and further optimization as informed from the clinical studies. However, this funding opportunity will not provide funds for conducting the clinical studies; applicants are encouraged to collaborate with NIAID-supported clinical trial networks or to develop other relationships to support the clinical studies. A clinical development plan describing means to initiate a clinical study during the first 5 years of award is a requirement of this FOA.

Full Announcement


Feasibility Studies to Build Collaborative Partnerships in Cancer Research (P20)

Deadline: March 19, 2015

The National Cancer Institute (NCI) invites NIH P20 grant applications for the implementation of collaborative partnership awards between Institutions serving communiites c with cancer health disparities and NCI-designated Cancer Centers (or groups of Centers).For the purpose of this funding opportunity announcement (FOA), "the Institutions" will refer to academic or other organizations serving communitieswith cancer health disparities. This FOA is designed to facilitate the planning and execution of focused collaborations in cancer-related research, training and career development, and education by supporting the creation of partnership frameworks and the conduct of pilot projects and pilot programs by investigators at the partnering institutions. A major goal of the NCI P20 partnership awards is to provide support for investigators at the Institutions to conduct cancer pilot projects and programs, which should allow awardees to obtain preliminary data that will lead to their submission of competitive grant applications for support by the NIH/NCI and/or other Federal/non-Federal sources of peer-reviewed funding.

Full Announcement


Opportunities for Collaborative Research at the NIH Clinical Center (U01)

Deadline: March 20, 2015

The goal of this funding opportunity announcement (FOA) is to support collaborative translational research projects aligned with NIH efforts to enhance the translation of basic biological discoveries into clinical applications that improve health. This opportunity is specifically to promote partnerships between NIH intramural investigators (e.g., those conducting research within the labs and clinics of the NIH) and extramural investigators (e.g., those conducting research in labs outside the NIH). It will provide support for extramural investigators to take advantage of the unique research opportunities available at the NIH Clinical Center by conducting research projects in collaboration with NIH intramural investigators.

Full Announcement


Vet-LIRN Cooperative Agreement Program to Expand and Validate Testing Methods for Food Contaminants in Animal Diagnostic Specimens (U18)

Deadline:  April 1, 2015

FDA developed the Veterinary Laboratory Investigation and Response Network (Vet- LIRN, formerly Vet-LRN) to increase the safety of human and animal health by investigating potential adverse events involving animal feed or animal drug contamination or adulteration. The testing of diagnostic specimens adds insight into investigations not routinely obtained from traditional food testing laboratories. Such investigations require detection methods that are validated for organs and diagnostic samples such as urine and feces, which are not typical food matrices. It is the purpose of this program to expand and validate detection methods among cooperative agreement laboratories. This activity is designed to increase the suite of validated methods available for testing during outbreaks or events. It is also designed to strengthen the collaborations and integration of the network laboratories to encourage seamless interactions during actual emergency related testing. Eligibility is limited to only Vet-LIRN network laboratories.

Full Announcement


Development and Testing of Novel Interventions to Improve HIV Prevention, Care, and Program Implementation

Deadline: May 7, 2015

This FOA is issued by the National institute on Drug Abuse (NIDA), National Institutes of Health for R34 applications, and provides resources to support (a) pilot or feasibility studies of new or adapted interventions to prevent HIV infection among populations where substance use may be a contributing factor; (b) pilot or feasibility studies of new or adapted interventions to improve the care of HIV infection among populations where substance use is prevalent, including interventions that integrate treatment for substance use disorders and HIV infection; or (c) pilot or feasibility studies to increase the scale, uptake, delivery, and/or quality of HIV prevention or care interventions with established evidence of efficacy.

Full Announcement


National Institute on Aging: Revision Requests for Active Alzheimer's Disease Core Centers (P30)

Deadline: May 7, 2015

The National Institute on Aging invites Revision applications (formerly called competing supplements) to ongoing NIA-supported Alzheimer's Disease Core Centers (P30) in order to expand the scope of the existing award. Revision applications should propose a new core. Revision applications may not request support beyond the end date of the Parent P30 award.

Full Announcement


Collaborative R01s for Clinical and Services Studies of Mental Disorders and AIDS (Collaborative R01)

Deadline: May 7, 2015

The National Institute of Mental Health (NIMH) seeks to support collaborative intervention trials in the treatment, prevention or rehabilitation of those with mental disorders and comorbid mental disorders. Support is also provided for other collaborative clinical studies, including, but not limited to, mental health services research, AIDS, genetics, and psychopathology. This Funding Opportunity Announcement (FOA) should be used when two or more sites are needed to complete the study. Accordingly, the collaborating studies share a specific protocol across the sites and are organized as such in order to increase sample size, accelerate recruitment, or increase sample diversity and representation. In studies with a large number of sites, it is expected that one site will be submitted as a coordinating site for data management and/or other centralized administration. For a linked set of collaborative R01s, each site has its own Program Director/Principal Investigator and the program provides a mechanism for cross-site coordination, quality control, database management, statistical analysis, and reporting.

Full Announcement


New Directions in Hematology Research (SHINE-II) (R01)

Deadline: May 7, 2015

This research Funding Opportunity Announcement (FOA), New Directions in Hematology Research (SHINE-II), is intended to promote innovative research initiatives that explore high impact, new directions of inquiry relevant to the hematology research mission of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). This new Funding Opportunity builds upon the objectives of an on-going program defined by PAS-10-046: Stimulating Hematology Investigation: New Endeavors (or SHINE). With the SHINE-II program, NIDDK invites investigator-initiated grant applications for pre-clinical, proof of principle research projects that are tightly focused and directed at validating novel concepts and approaches that promise to open up new pathways for discovery. Research applications submitted under this FOA should be more limited in scope (a single central aim) and duration (1-3 years) than typical R01 grant applications.

Full Announcement


Team-Based Design in Biomedical Engineering Education (R25)

Deadline:  May 13, 2015

This FOA, issued by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), encourages applications from institutions that propose to establish new or to enhance existing team-based design courses in undergraduate Biomedical Engineering departments or programs. This FOA targets undergraduate students at the senior level but may also include junior undergraduates and first-year graduate students. Courses that address innovative and/or ground-breaking development, multidisciplinary/interdisciplinary training and clincial immersion are especially encouraged.

Full Announcement


Limited Competition: Global Health Research and Research Training eCapacity Initiative (R25)

Deadline:  May 15, 2014

The goal of this initiative is to develop innovative educational approaches that enhance research capacity at low and middle income country (LMIC) institutions by expanding the use of information and communication technology (ICT) in global health research and research training. This funding opportunity aims to leverage the research capacity established by current or former Fogarty International Center research and research training grants through direct links with these awards.

Full Announcement


NIH Summer Research Experience Programs (R25)

Deadline:  May 21, 2015

The purpose of the NIH Summer Research Experience Program (referred to as the Summer Research Program) is to provide a high quality research experience for high school and college students and for science teachers during the summer academic break. The NIH expects that such programs will: help attract young students to careers in science; provide opportunities for college students to gain valuable research experience to help prepare them for graduate school; and enhance the skills of science teachers and enable them to more effectively communicate the nature of the scientific process to their students. The programs would also contribute to enhancing overall science literacy. Summer Research Programs that expand and complement existing summer educational and training programs are encouraged. Note: Not all participating Institutes and Centers (ICs) support all aspects of this program. Therefore, prospective applicants must consult the Table of IC-Specific Information, Requirements and Staff Contacts in this announcement to determine if your application will be accepted for review, and should contact staff at the relevant IC (see also Section VII) to discuss the proposed Program.

Full Announcement 


International Research Ethics Education and Curriculum Development Award (R25)

Deadline: May 22, 2015

The goal of this initiative is strengthen research ethics capacity in low- and middle-income countries (LMICs) through increasing the number of scientists, health professionals and relevant academics from these countries with in-depth knowledge of the ethical principles, processes and policies related to international clinical and public health research as well as the critical skills to develop research ethics education, ethical review leadership and expert consultation to researchers, their institutions, governments and international research organizations.

Full Announcement


Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Predoctoral Training Program in Systems Developmental Biology (T32)

Deadline: May 25, 2015

This Funding Opportunity Announcement (FOA) issued by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) encourages applications for predoctoral NRSA T32s to provide research training in systems biology of developmental biology and/or structural birth defects research.

Full Announcement


Postdoctoral Training Program in Obstetric and Pediatric Pharmacoepidemiology (T32)

Deadline:  May 25, 2015

This funding opportunity announcement (FOA) encourages applications from organizations that propose creative and innovative institutional research training programs in the mission area(s) of the NICHD. The purpose of the training program is to help ensure that a diverse pool of highly trained scientists is available in appropriate scientific disciplines to address the nations biomedical, behavioral, and clinical research needs. The goals of this training program are: (1) to encourage and support training in pediatric and/or obstetric pharmacoepidemiology; and (2) to produce a well-qualified cadre of academic investigators who are capable of conducting pharmacoepidemiologic research in children and/or pregnant women.

Full Announcement


MARC Undergraduate Student Training in Academic Research (U-STAR) National Research Service Award (NRSA) Institutional Research Training Grant (T34)

Deadline:  May 25, 2015

The purpose of the Minority Access to Research Careers (MARC) Undergraduate Student Training in Academic Research (U-STAR) Institutional Ruth L. Kirschstein National Research Service Award (NRSA) Training program is to assist undergraduate institutions to increase the number of well-prepared underrepresented (UR) students who, within three years of graduation, matriculate into competitive/research active Ph.D. or combined M.D.-Ph.D. programs in the biomedical and behavioral sciences, go on to research careers and will be available to participate in NIH-funded research. The program provides grants to institutions with significant enrollment of students from groups underrepresented in the biomedical and behavioral sciences that propose well-integrated developmental activities designed to strengthen students academic preparation, research training and professional skills that are critical to the completion of the Ph.D. degree in the biomedical and behavioral sciences.

Full Announcement


Revisions for Early-Stage Development of Informatics Technology (R01)

Deadline: June 18, 2015

The purpose of this Funding Opportunity Announcement (FOA) is to encourage revision applications (formerly called "competing revisions") from currently funded NCI R01 and R37 (MERIT) research projects for early-stage development of enabling informatics technologies to improve the acquisition, management, analysis, and dissemination of data and knowledge. As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Initiative, this FOA aims to promote interdisciplinary collaboration in the development of innovative computational methods and informatics approaches that are essential for cancer research on all fronts to accelerate scientific discovery and ultimately translate data into knowledge and clinical practice. Applications that focus on data processing and analysis or mathematical/statistical modeling alone without new technology development are not appropriate for this FOA.

Full Announcement


Advanced Development of Informatics Technology (U24)

Deadline: June 18, 2015

The purpose of this Funding Opportunity Announcement (FOA) is to invite Cooperative Agreement (U24) applications for advanced development and enhancement of emerging informatics technologies to improve the acquisition, management, analysis, and dissemination of data and knowledge in cancer research. An emerging informatics technology is defined as one that has passed the initial prototyping and pilot development stage, has demonstrated potential to have a significant and broader impact, has compelling reasons for further improvement and enhancement, and has not been widely adopted in the cancer research field. If successful, these technologies would accelerate research in cancer biology, cancer treatment and diagnosis, cancer prevention, cancer control and epidemiology, and/or cancer health disparities. This FOA is one component of the NCI's Informatics Technology for Cancer Research (ITCR) Initiative whose central mission is to promote research-driven informatics technology development.Potential applicants who are interested in early-stage development should consult companion FOAs listed on the previous page.Applications that focus on informatics data processing and analysis or mathematical/statistical modeling alone without informatics technology development are not appropriate for this FOA.

Full Announcement


Early-Stage Development of Informatics Technology (U01)

Deadline: June 18, 2015

The purpose of this Funding Opportunity Announcement (FOA) is to invite Cooperative Agreement (U01) applications for the development of enabling informatics technologies to improve the acquisition, management, analysis, and dissemination of data and knowledge in cancer research. As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Initiative, this FOA focuses on early-stage development from prototyping to hardening and adaptation. The central mission of the ITCR is to promote research-driven informatics technology development. In order to be successful, proposed development plans must have a clear rationale on why the proposed technology is needed and how it will benefit the cancer research community. In addition, mechanisms to solicit feedback from users and collaborators throughout the development process should be included. Applications that focus on data processing and analysis or mathematical/statistical modeling alone without new technology development are not appropriate for this FOA.

Full Announcement


Revisions for Early-Stage Development of Informatics Technology (P01)

Deadline: June 18, 2015

The purpose of this Funding Opportunity Announcement (FOA) is to invite revisions (formerly called "competing revisions") from currently funded NCI P01 program projects for early-stage development of enabling informatics technologies to improve the acquisition, management, analysis, and dissemination of data and knowledge. As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Initiative, this FOA aims to promote interdisciplinary collaboration in the development of innovative computational methods and informatics approaches that are essential for cancer research on all fronts to accelerate scientific discovery and ultimately translate data into knowledge and clinical practice. Applications that focus on data processing and analysis or mathematical/statistical modeling alone without new technology development are not appropriate for this FOA.

Full Announcement


Paul Calabresi Career Development Award for Clinical Oncology (K12)

Deadline:  June 18, 2015

This funding opportunity announcement (FOA) encourages applications for institutional research career development (K12) programs from applicant organizations that propose to promote the training and career development of clinical trials researchers. The purpose of the Paul Calabresi Career Development Award for Clinical Oncology (K12) is to increase the number of clinicians (M.D.s, D.O.s, Pharm.D.s, nurses with Ph.D.s or equivalent) and Ph.D. scientists who are trained to design and test clinical therapeutic research protocols (pilot/Phase I, Phase II, and Phase III clinical trials), conduct patient-oriented cancer therapeutic research in team research environments, and to support the career development of investigators who have made a commitment to focus their research endeavors on patient-oriented research.

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Research in latent tuberculosis infection (LTBI) in the setting of HIV Co-Infection (R01)

Deadline: July 24, 2015

The National Institute of Allergy and Infectious Diseases, at the National Institutes of Health invites grant applications which propose research to increase our understanding of the microbiologic adaptive mechanisms, host immunologic factors, and their interactions involved in the development, maintenance, and activation of latent tuberculosis infections (LTBI) with a focus on HIV co-infection.

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Limited Competition: Fogarty HIV Research Training Program for Low-and Middle-Income Country Institutions (D43)

Deadline:  July 30, 2015

The purpose of this FOA is to encourage applications for research training programs to develop and strengthen the scientific leadership and expertise needed for HIV-related research at eligible Low-and Middle-Income Country (LMIC) institutions.

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Limited Competition: Planning Grant for Fogarty HIV Research Training Program for Low-and Middle-Income Country institutions (D71)

Deadline:  July 30, 2015

The purpose of this FOA is to encourage institutions in eligible low-and middle-income countries (LMIC) to submit an application for a planning grant under the Fogarty HIV Research Training Program. This program supports research training that will strengthen the HIV research capacity of institutions in low-and middle-income countries (LMIC). The planning grant application must propose a plan to develop the components necessary for an application for a research training program to submit to D43 FOA (PAR-13-126). In developing an application for a planning grant, applicants need to be familiar with the objectives and special requirements of the research training program as defined in the D43 FOA.

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Limited Competition: Training Programs for Critical HIV Research Infrastructure for Low- and Middle-Income Country Institutions (G11)

Deadline:  July 30, 2015

The purpose of this FOA is to encourage U.S. institutions with research collaborations at low-and middle-income country (LMIC) institutions to submit applications for training programs to strengthen the leadership and expertise in selected critical research infrastructure areas at their collaborating LMIC institutions.

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AHRQ Grants for Health Services Research Dissertation Program

Deadline: August 1, 2015

The overall goal of the AHRQ Health Services Research Dissertation Grant Program is to help ensure that a diverse pool of highly trained health services researchers is available in adequate numbers and appropriate research areas to address the research mission and priorities of AHRQ. This program is authorized by 42 U.S.C. 299a(b), which provides that AHRQ may provide training grants in the field of health services research. The mission of AHRQ is to improve the quality, safety, efficiency, and effectiveness of health care for all Americans in the United States.

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Developing and Improving Institutional Animal Resources (G20)

Deadline:  August 3, 2015

This FOA encourages applications from biomedical research institutions that propose to renovate, repair, or improve individual animal resources. The major objective of this program is to upgrade animal facilities to support the conduct of biomedical and/or behavioral research. Support can be requested to alter and renovate (A&R) the animal facilities, as well as to improve the animal care equipment in the facility. It is expected that all award funds will be expended expeditiously and that applicants will consider the use of sustainable design technologies and design approaches.

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Mentored Research Scientist Development Award (K01)

Deadline:  September 2, 2015

The purpose of the K01 is to provide support and 75% “protected time” for an intensive, supervised (mentored) career development experience in occupational health and safety research leading to research independence. The goal of the NIOSH Mentored Research Scientist Development Award (K01) is to help ensure the availability of an adequate numbers of highly trained scientists and educators to address occupational safety and health critical issues.
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Functions of Skeletal Muscle beyond Contraction

Deadline: September 7, 2015

With this funding opportunity announcement, the National Institute of Arthritis and Musculoskeletal and Skin Diseases encourages applications for support of innovative, projects aimed at studying the spectrum of activities of skeletal muscle in health and disease that are beyond its role in contraction and locomotion. These activities include endocrine and paracrine functions of skeletal muscle, resting muscle thermogenesis, sensing of biomechanical stimuli, storing amino acids, regulating systemic metabolism, etc. Advancing understanding of these important functions of muscle may lead to novel strategies for the prevention or treatment of common conditions such as cachexia, obesity, diabetes and sarcopenia.

Full Announcement


Functions of Skeletal Muscle beyond Contraction

Deadline: September 7, 2015

With this funding opportunity announcement, the National Institute of Arthritis and Musculoskeletal and Skin Diseases encourages applications for support of innovative, projects aimed at studying the spectrum of activities of skeletal muscle in health and disease that are beyond its role in contraction and locomotion. These activities include endocrine and paracrine functions of skeletal muscle, resting muscle thermogenesis, sensing of biomechanical stimuli, storing amino acids, regulating systemic metabolism, etc. Advancing understanding of these important functions of muscle may lead to novel strategies for the prevention or treatment of common conditions such as cachexia, obesity, diabetes and sarcopenia.

Full Announcement


Functions of Skeletal Muscle beyond Contraction

Deadline: September 7, 2015

With this funding opportunity announcement, the National Institute of Arthritis and Musculoskeletal and Skin Diseases encourages applications for support of innovative, exploratory/developmental projects aimed at studying the spectrum of activities of skeletal muscle in health and disease that are beyond its role in contraction and locomotion. These activities include endocrine and paracrine functions of skeletal muscle, resting muscle thermogenesis, sensing of biomechanical stimuli, storing amino acids, regulating systemic metabolism, etc. Advancing understanding of these important functions of muscle may lead to novel strategies for the prevention or treatment of common conditions such as cachexia, obesity, diabetes and sarcopenia.

Full Announcement


Estimating the Economic Costs of Alzheimer’s Disease and Related Dementias

Deadline: September 7, 2015

Alzheimer’s disease and other forms of dementia are widely believed to impose great economic costs on society, but the magnitude of those costs is unclear. This Funding Opportunity Announcement (FOA) encourages research on the economic costs of Alzheimer’s disease and related dementias, including direct and indirect costs to public and private health care payers, families and other informal caregivers, as well as labor market costs from reduced productivity or labor force participation.

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Estimating the Economic Costs of Alzheimer’s Disease and Related Dementias

Deadline: September 7, 2015

Alzheimer’s disease and other forms of dementia are widely believed to impose great economic costs on society, but the magnitude of those costs is unclear. This Funding Opportunity Announcement (FOA) encourages research on the economic costs of Alzheimer’s disease and related dementias, including direct and indirect costs to public and private health care payers, families and other informal caregivers, as well as labor market costs from reduced productivity or labor force participation.

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Estimating the Economic Costs of Alzheimer's Disease and Related Dementias

Deadline: September 7, 2015

Alzheimers disease and other forms of dementia are widely believed to impose great economic costs on society, but the magnitude of those costs is unclear. This Funding Opportunity Announcement (FOA) encourages research on the economic costs of Alzheimer's disease and related dementias, including direct and indirect costs to public and private health care payers, families and other informal caregivers, as well as labor market costs from reduced productivity or labor force participation.

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Physical activity and weight control interventions among cancer survivors: Effects on biomarkers of prognosis and survival

Deadline: September 7, 2015

This Funding Opportunity Announcement (FOA) encourages transdisciplinary and translational research that will identify specific biological or biobehavioral pathways through which physical activity and/or weight control (either weight loss or avoidance of weight gain) may affect cancer prognosis and survival. Research applications must test the effects of physical activity or weight control or both interventions on biomarkers of cancer prognosis among cancer survivors identified by previous animal or observational research, which may include but are not limited to intervention-induced changes in sex hormones, insulin or insulin-like growth factors or their binding proteins, insulin resistance, glucose metabolism, leptin and other adipokines, immunologic or inflammatory factors, oxidative stress and DNA damage or repair capacity, angiogenesis, or prostaglandins.

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Ancillary Studies to Major Ongoing Clinical Research Studies to Advance Areas of Scientific Interest within the Mission of the NIDDK (R01)

Deadline: September 7, 2015

The purpose of this Funding Opportunity Announcement (FOA) is to encourage Research Project Grant (R01) applications from qualified investigators to conduct ancillary studies to major ongoing research studies, including clinical trials, epidemiological studies and disease databases (described as parent studies) supported by the National Institute of Diabetes and Digestive and Kidney Diseases, other Institutes and Centers of the National Institutes of Health, other government agencies and the private sector. The proposed ancillary study must be designed to advance the scientific research mission of the NIDDK by focusing on diseases and areas of direct interest of the Institute. The scientific areas funded by the NIDDK may be found at the following website: htttp:www2.niddk.nih.gov/research. Important elements of this FOA are that the parent study must be ongoing, the subject of inquiry must be within the mission and interest of the NIDDK, the ancillary study must be approved by the appropriate governing body of the parent study, and the proposed study collects new information from enrolled study participant and/or assays of existing or new biologic samples.

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Lymphatics in Health and Disease in the Digestive, Urinary, Cardiovascular and Pulmonary Systems

Deadline: September 7, 2015

This FOA is to encourage Research Project Grant (R01) applications for research into aspects of lymphatic vessel physiology and pathophysiology related to health and disease of digestive system and urinary tract organs, and cardiovascular and pulmonary systems; in resolution of thromboembolic events; and inflammation and immune responses as they relate to these diseases. However, studies with the major focus on immune mechanisms will not be considered responsive. Studies to understand the factors that control local lymphatic vessel functional anatomy and physiology during health or disease in these organs/systems, and the mechanisms by which alterations of lymphatic vessel function affect organ function, are of interest.

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Pilot Intervention and Services Research Grants (R34)

Deadline: September 7, 2015

The purpose of this Funding Opportunity Announcement (FOA) is to encourage research on 1) the development and/or pilot testing of new or adapted interventions, 2) the adaptation and/or pilot testing of interventions with demonstrated efficacy for use in broader scale effectiveness trials, or 3) innovative services research directions that require preliminary testing or development. The R34 award mechanism provides resources for evaluating the feasibility, tolerability, acceptability and safety of novel approaches to improving mental health and modifying health risk behavior, and for obtaining the preliminary data needed as a pre-requisite to a larger-scale (efficacy or effectiveness) intervention or services study. NIMH intervention and services research is aimed at preventing or ameliorating mental disorders, emotional or behavioral problems, the co-occurrence of mental, physical and substance abuse problems, HIV infections, and the functional consequences of these problems across the life span. NIAAA prevention, treatment, and services research is aimed at preventing or ameliorating alcohol use disorders, related emotional or behavioral problems, and the co-occurrence of other mental, physical, and substance abuse problems, HIV/AIDS, and the functional consequences of these problems across the life span.

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AIDS-Science Track Award for Research Transition (R03)

Deadline: September 7, 2015

This funding opportunity announcement (FOA) by the National Institute on Drug Abuse seeks to facilitate the entry of both newly independent and early career investigators to the area of drug abuse research on HIV/AIDS. This FOA, AIDS–Science Track Award for Research Transition (A-START), encourages Small Research Grant (R03) applications to support research projects on drug abuse and HIV/AIDS that can be carried out in a short period of time with limited resources. Applications under this FOA are welcomed from all areas of HIV/AIDS research that NIDA supports.

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NIDCR Dentist Scientist Pathway to Independence Award (K99/R00)

Deadline: September 7, 2015

The primary purpose of the Pathway to Independence Award (K99/R00) program is to increase and maintain a strong cohort of new and talented NIH-supported independent investigators. The program is designed to facilitate a timely transition from a mentored postdoctoral research position to a stable independent research position with independent NIH or other independent research support at an earlier stage than is currently the norm.

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Small Grants for New Investigators to Promote Diversity in Health-Related Research (R03)

Deadline: September 7, 2015

The purpose of this funding opportunity announcement (FOA) is to provide support for New Investigators from backgrounds nationally underrepresented in biomedical research to conduct small research projects in the scientific mission areas of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), the National Institute of Mental Health (NIMH) and the Office of Dietary Supplements (ODS). The scientific mission areas of the Institutes and Office are: NIDDK -diabetes, endocrinology, metabolism, digestive diseases, hepatology, obesity, nutrition, kidney, urology, or hematology; NIMH factors contributing to mental disorders, the trajectories of mental disorders, pre-emption and treatment of mental disorders, identify and improve interventions for mental illness; and ODS all types of research in which the primary emphasis is the investigation of dietary supplements and/or their ingredients.

Full Announcement


NIDA Research Education Program for Clinical Researchers and Clinicians (R25)

Deadline: September 7, 2015

The NIDA Research Education Program will support research education for those in clinically focused careers, in a topic area related to substance use/abuse/addiction. Participants (those receiving the research education) should be training for careers as clinical researchers, clinicians/service providers, or optimally, a combination of the two. This mechanism may not be used for support of non-research related clinical training.

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NIDA Mentored Clinical Scientists Development Program Award in Drug Abuse and Addiction (K12)

Deadline:  September 7, 2015

This funding opportunity announcement (FOA) encourages applications for institutional research career development (K12) programs that propose to support intensive supervised research training and career development experiences for clinician scientists (scholars) leading to research independence in the area of drug abuse and addiction. For this FOA, clinician scientists may include (but are not limited to) physicians, clinical psychologists, epidemiologists, doctoral-level social workers, pharmacists, and behavioral scientists. Scholars are expected to be supported for 3-5 years on consecutive 12-month appointments. Candidates selected for support as scholars must hold a doctorate and commit a minimum of 9 person-months (equivalent to 75% of full-time professional effort) to conducting clinical research and career development activities associated with the proposed program.

Full Announcement 


NIOSH Small Research Program

Deadline: September 8, 2015

The purpose of this grant program is to develop an understanding of the risks and conditions associated with occupational diseases and injuries, to explore methods for reducing risks and for preventing or minimizing exposure to hazardous conditions in the workplace, and to translate significant scientific findings into prevention practices and products that will effectively reduce work-related illnesses and injuries.

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NIOSH Exploratory/Developmental Grant Program (R21)

Deadline:  September 8, 2015

The purpose of this grant program is to develop an understanding of the risks and conditions associated with occupational diseases and injuries, to explore methods for reducing risks and for preventing or minimizing exposure to hazardous conditions in the workplace, and to translate significant scientific findings into prevention practices and products that will effectively reduce work-related illnesses and injuries.

Full Announcement 


Time-Sensitive Obesity Policy and Program Evaluation

Deadline: September 10, 2015

This Funding Opportunity Announcement (FOA) is issued by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Cancer Institute (NCI), National Institute on Aging (NIA), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), and the Office of Behavioral and Social Sciences Research (OBSSR), at the National Institutes of Health (NIH). This announcement establishes an accelerated review/award process to support time-sensitive research to evaluate a new policy or program expected to influence obesity related behaviors (e.g., dietary intake, physical activity, or sedentary behavior) and/or weight outcomes in an effort to prevent or reduce obesity. This FOA is intended to support research where opportunities for empirical study are, by their very nature, only available through expedited review and funding. All applications to this FOA must demonstrate that the evaluation of an obesity related policy and /or program offers an uncommon and scientifically compelling research opportunity that will only be available if the research is initiated with minimum delay. For these reasons, applications in response to this time-sensitive FOA are eligible for only one submission. It is intended that eligible applications selected for funding will be awarded within 3-4 months after the application submission/receipt date. However, administrative requirements and other unforeseen circumstances may delay issuance dates beyond that timeline.

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Countermeasures Against Chemical Threats (CounterACT) Cooperative Research Projects (U01)

Deadline:  September 16, 2015

This Funding Opportunity Announcement (FOA) encourages grant applications for Countermeasures Against Chemical Threats (CounterACT) Cooperative Research Projects (U01s). The mission of the CounterACT U01 program is to develop new and improved therapeutics for chemical threats. Chemical threats are toxic chemicals that could be used in a terrorist attack or accidentally released from industrial production, storage or shipping. They include traditional chemical warfare agents, toxic industrial chemicals, and pesticides. Applicants are encouraged to contact the Program Officials listed in this FOA to determine if their proposed threat agent(s) or countermeasure(s) is of high program priority for one of the participating Institutes. The scope of the research to be supported includes target and candidate identification and characterization, through candidate optimization and demonstration of in vivo efficacy, through Investigational New Drug (IND) submission when appropriate. Each project must include milestones that create discrete go or no-go decision points in a progressive translational study plan.

Full Announcement 


Countermeasures Against Chemical Threats (CounterACT) Cooperative Research Projects (U01)

Deadline:  September 16, 2015

This Funding Opportunity Announcement (FOA) encourages grant applications for Countermeasures Against Chemical Threats (CounterACT) Cooperative Research Projects (U01s). The mission of the CounterACT U01 program is to develop new and improved therapeutics for chemical threats.

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Biophysical and Biomechanical Aspects of Embryonic Development (R21)

Deadline:  September 17, 2015

This Funding Opportunity Announcement (FOA) is intended to encourage innovative and high risk/impact research in the area of physics/mechanics of embryonic development to be explored in model organisms. The research proposed under this program can explore approaches and concepts new to the area of developmental tissue mechanics, research and development of new technologies, or initial research and development of data upon which significant future research may be built. The focus of this FOA is to promote research aimed at generating new and critical information about tissue mechanics relevant to vertebrate development and understanding the basis for developmental disorders. While minimal or no preliminary data are expected to be described, applications should clearly indicate the significance of the proposed work, that the proposed research and/or development is scientifically sound, that the qualifications of the investigators are appropriate, and that resources available to the investigators are adequate.

Full Announcement 


Biophysical and Biomechanical Aspects of Embryonic Development (R01)

Deadline:  September 17, 2015

This Funding Opportunity Announcement (FOA) encourages Research Project Grant (R01) applications from institutions/organizations that propose to advance our knowledge in the area of the physics and mechanics of embryonic development. Applicants must propose hypothesis-driven developmental research with the prospect of gaining new and critical information about tissue mechanics relevant to vertebrate development and understanding the basis for developmental disorders. Investigators are encouraged to explore approaches and concepts new to the area of developmental tissue mechanics, and use newly developed techniques superior to the ones currently used in the field. It should be noted that applications using the NIH R01 grant mechanism will require sufficient preliminary data to substantiate the validity of the proposed research and feasibility of new technologies or tools.

Full Announcement 


Dual Purpose with Dual Benefit: Research in Biomedicine and Agriculture Using Agriculturally Important Domestic Animal Species (R01)

Deadline:  September 24, 2015

This interagency Funding Opportunity Announcement (FOA) issued by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) and the National Institute of Food and Agriculture (USDA-NIFA) is to invite the submission of grant applications that utilize agriculturally important domestic animal species to improve human health through the advancement of basic and translational research deemed highly relevant to both agricultural and biomedical research. This initiative is designed to facilitate and encourage comparative medicine research studies through the careful selection and refinement of farm animal models that mimic human developmental, physiological and etiological processes to better understand disease origins and improve assisted reproduction efficiencies. The anticipated outcomes include both the elucidation of fundamental information relevant for the improvement of human health and an increase in food animal production and improvement in animal health and product quality. It is envisioned that each application will address mission-relevant areas of both agencies.

Full Announcement


AHRQ Health Services Research Demonstration and Dissemination Grants (R18)

Deadline: September 25, 2015

The Research Demonstration and Dissemination Grant (R18) is an award made by AHRQ to an institution/organization to support a discrete, specified health services research project. The project will be performed by the named investigator and study team. The R18 research plan proposed by the applicant institution/organization must be related to the mission and portfolio priority research interests of AHRQ.

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Renewal of Centers of Biomedical Research Excellence [COBRE](P20)

Deadline:  September 25, 2015

The National Institute of General Medical Sciences (NIGMS) invites renewal applications from eligible Centers of Biomedical Research Excellence (COBRE). The objective of the COBRE initiative is to strengthen an institution's biomedical research infrastructure through the establishment of a thematic, multi-disciplinary center and to enhance the ability of investigators to compete independently for National Institutes of Health (NIH) individual research grants or other external peer-reviewed support. COBRE awards are supported through the Institutional Development Award (IDeA) Program, which aims to foster health-related research by increasing the competitiveness of investigators at institutions located in IDeA states.

Full Announcement


Health Services Research Demonstration and Dissemination Projects for Prevention and Management of Healthcare-Associated Infections (R18)

Deadline: September 26, 2015

This FOA issued by AHRQ solicits grant applications for funding to conduct Health Services Research Demonstration and Dissemination Projects (R18) that propose to address strategies and approaches for prevention, reduction, and effective management of HAIs. The FOA describes the broad areas of HAI research for which funds are available to support Health Services Research Demonstration and Dissemination Projects.

Full Announcement


Research Supplements to Promote Diversity in Health-Related Research (Admin Supp)

Deadline:  September 29, 2015

The National Institutes of Health (NIH) and the Centers for Disease Control and Prevention (CDC) hereby notify Program Director(s)/Principal Investigator(s) (PD(s)/PI(s)) holding specific types of NIH research grants, listed in the full Funding Opportunity Announcement (FOA) that funds are available for administrative supplements to improve the diversity of the research workforce by supporting and recruiting students, postdoctorates, and eligible investigators from groups that have been shown to be underrepresented in health-related research. This supplement opportunity is also available to PD(s)/PI(s) of research grants who become disabled and need additional support to accommodate their disability in order to continue to work on the research project. Administrative supplements must support work within the scope of the original project.

Full Announcement


Research Supplements to Promote Re-Entry into Biomedical and Behavioral Research Careers (Admin Supp)

Deadline:  September 29, 2015

The Office of Research on Womens Health (ORWH), participating Institutes and Centers (ICs) of the National Institutes of Health (NIH), and the Office of Dietary Supplements (ODS) announce the continuation of the program for administrative supplements to research grants to support individuals with high potential to re-enter an active research career after an interruption for family responsibilities or other qualifying circumstances. The purpose of these supplements is to encourage such individuals to re-enter research careers within the missions of all the program areas of NIH. This program will provide administrative supplements to existing NIH research grants for the purpose of supporting full-time or part-time research by these individuals to update their existing research skills and knowledge.

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NIDCD Clinical Research Center Grant (P50)

Deadline: October 1, 2015

The National Institute on Deafness and Other Communication Disorders (NIDCD) invites applications for Clinical Research Center Grants designed to advance the diagnosis, prevention, treatment, and amelioration of human communication disorders. For this announcement, Clinical Research is defined as research involving individuals with communication disorders or data/tissues from individuals with a communication disorder. Examples of such research include but are not limited to, studies of the prevention, pathogenesis, pathophysiology, diagnosis, treatment, management or epidemiology of a disease or disorder of hearing, balance, smell, taste, voice, speech, or language.

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NIDCD Research Core Centers (P30)

Deadline: October 15, 2015

The NIDCD P30 Core Center contains one or more research-serving cores providing centralized resources and facilities for funded R01 research projects. Although no funds are provided for direct support of research projects, a P30 helps to integrate and promote research in existing funded projects, and may include multi-disciplinary and regional collaborations. A Core Center must be an identifiable organizational unit either within a single grantee institution or representing a consortium of cooperating institutions (e.g., geographic or web-based). The Center may serve as an intellectual hub to stimulate cooperative research, to increase the effectiveness, capabilities or productivity of current research, and/or to promote new research directions through collaborations. Individual research cores of the Core Center may provide for sharing technical expertise or centralizing labor-intensive tasks common among several investigators (PD(s)/PI(s)); staffing, training and maintenance of shared equipment or resources, including tools or staffing to enhance activities such as recruitment databases for clinical projects; or problem-solving through innovative technical solutions using the most current methodologies. NIDCD P30 funds do not provide patient services, support unfunded pilot studies, or facilitate research other than for funded user projects, unless directly related to advancing the potential of the Core Center itself. P30s are encouraged to provide benefits to other core centers or the larger community through sharing data or technology.

Full Announcement


Unveiling the Genome: Genetic Architecture of Severe Mental Disorders Revealed (Collaborative U01)

Deadline:  October 15, 2015

The purpose of this Funding Opportunity Announcement (FOA) is to support a consortium of collaborative projects, with a minimum of two sites, that propose to use cutting edge technologies to generate and analyze whole genome sequencing (WGS) data from either case control or family samples in order to elucidate the full genetic architecture underlying susceptibility to severe mental disorders. Insights into the genetic architecture underlying susceptibility to severe mental disorders will be achieved through implementation of state of the art WGS assays and innovative/novel statistical methods.

Full Announcement


National Cooperative Drug Discovery/Development Groups (NCDDG) for the Treatment of Mental Disorders, Drug or Alcohol Addiction (U19)

Deadline: October 22, 2015

The purpose of the National Cooperative Drug Discovery/Development Group (NCDDG) Program is to create multidisciplinary research groups or partnerships for the discovery of pharmacological agents to treat and to study mental illness or drug or alcohol addiction. The objectives of this program are to: accelerate innovative drug discovery; develop pharmacologic tools for basic and clinical research on mental disorders, or drug or alcohol addiction; develop and validate models for evaluating novel therapeutics for mental disorders; and support early phase human clinical testing to rapidly assess the safety and efficacy of promising drug candidates and new indications for IND-ready agents for the treatment of mental disorders or alcohol addiction. The National Institute of Mental Health (NIMH), the National Institute on Drug Abuse (NIDA), and the National Institute on Alcohol Abuse and Alcoholism (NIAAA) encourage applications to advance the discovery, preclinical development, and proof of concept testing of new, rationally-based candidate agents to treat mental disorders or drug or alcohol addiction, and to develop novel ligands as tools to further characterize existing or to validate new drug targets. Partnerships between academia and industry are strongly encouraged.

Full Announcement


National Cooperative Drug Discovery/Development Groups (NCDDG) for the Treatment of Mental Disorders, Drug or Alcohol Addiction (UM1)

Deadline: October 22, 2015

The purpose of the National Cooperative Drug Discovery/Development Group (NCDDG) Program is to create multidisciplinary research groups or partnerships for the discovery of pharmacological agents to treat and to study mental illness, drug or alcohol addiction. The objectives of this program are to: accelerate innovative drug discovery; develop pharmacologic tools for basic and clinical research on mental disorders, or drug or alcohol addiction; develop and validate models for evaluating novel therapeutics for mental disorders; and support early phase human clinical testing to rapidly assess the safety and efficacy of promising drug candidates and new indications for IND-ready agents for the treatment of mental disorders or alcohol addiction. The National Institute of Mental Health (NIMH), the National Institute on Drug Abuse (NIDA), and the National Institute on Alcohol Abuse and Alcoholism (NIAAA) encourage applications to advance the discovery, preclinical development, and proof of concept testing of new, rationally based candidate agents to treat mental disorders or drug or alcohol addiction, and to develop novel ligands as tools to further characterize existing or to validate new drug targets. Partnerships between academia and industry are strongly encouraged.

Full Announcement


Developing a Point-of-Care Device for the Diagnosis of Sickle Cell Disease in Low Resource Settings SBIR (R43/ R44)

Deadline:  October 23, 2015

This FOA encourages applications that propose to develop a point of care (POC) device for the diagnosis of sickle cell disease (SCD) in infants and young children in low-income and low-resource settings. The aim of this program is to provide rapid diagnosis of SCD to children such that appropriate therapy can be given to reduce the risk of future complications.
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NIDCD Small Grant Program (R03)

Deadline: October 28, 2015

The NIDCD Small Grant Program (R03) is intended to support basic and clinical research of scientists who are beginning to establish an independent research career. It cannot be used for thesis or dissertation research. The research must be focused on one or more of the areas within the biomedical and behavioral scientific mission of the NIDCD: hearing, balance, smell, taste, voice, speech, or language. The NIDCD R03 grant mechanism supports different types of projects including secondary analysis of existing data; small, self-contained research projects; development of research methodology; translational research; outcomes research; and development of new research technology. Irrespective of the type of project, the intent of the NIDCD R03 is for the Program Director(s)/Principal Investigator(s) (PD(s)/PI(s) to obtain sufficient preliminary data for a subsequent R01 application.

Full Announcement


Bridging the Gap Between Cancer Mechanism and Population Science (U01)

Deadline: November 4, 2015

The purpose of this Funding Opportunity Announcement (FOA) is to encourage applications for projects that bridge biological mechanism to population level scales. By incorporating insights and data from one end of the cancer research spectrum into the framework of the other, projects should be able to cross-validate data gathered at different scales, and explore links between basic biology, population science, and potential health applications in treatment, prevention, diagnosis, and/or screening. Proposed projects should pose a challenging cancer research question that can be addressed by connecting these two ends of the research spectrum that would be difficult to address or explain through biological or epidemiological investigation alone. Only a single cohesive project integrating aspects from these two areas is allowed in each application.

Full Announcement


AHRQ Health Services Research Projects (R01)

Deadline: November 5, 2015

The Research Project Grant (R01) is an award made by AHRQ to an institution/organization to support a discrete, specified health services research project. The project will be performed by the named investigator and study team. The R01 research plan proposed by the applicant institution/organization must be related to the mission and portfolio priority research interests of AHRQ.

Full Announcement


Large Research Projects for Prevention and Management of Healthcare-Associated Infections (R01)

Deadline: November 6, 2015

This FOA issued by AHRQ solicits grant applications for funding to conduct Large Research Projects (R01) that propose to advance the base of knowledge for detection, prevention, reduction, and effective management of HAIs. The FOA describes the broad areas of HAI research for which funds are available to support Large Research Projects.

Full Announcement


Collaborative Research in Integrative Cancer Biology (U01)

Deadline:  November 13, 2015

The purpose of this Funding Opportunity Announcement (FOA) is to encourage new research into integrative cancer biology by fostering collaborations between investigators currently supported through the Integrative Cancer Biology Program (ICBP) and those currently unaffiliated with the ICBP. These collaborative projects should leverage the existing expertise and resources from within the ICBP research community and combine those with new approaches, technologies or methods to address compelling cancer questions. Therefore, the proposed research projects must involve partnerships between investigators currently supported by ICBP and investigators currently unaffiliated with the program. Applications that focus on projects which neither involve integrative cancer biology research, nor expand individual ICBP investigators' research by adding additional expertise, resources, or approaches, or without affiliation to existing ICBP personnel, are not appropriate to this FOA.

Full Announcement 


Innovative Assays to Quantify the Latent HIV Reservoir (R21)

Deadline:   November 13, 2013

The purpose of this Funding Opportunity Announcement (FOA) is to support research on new or improved methods for quantifying latently infected cells in HIV-positive individuals on effective antiretroviral therapy. Quantifying latent HIV reservoirs is critical to evaluating strategies to cure HIV infection in vivo. The current gold-standard method involves a limiting dilution viral outgrowth assay that is slow, resource-intensive, and relatively imprecise. A molecular assay to accurately detect replication-competent provirus, or a viral outgrowth assay with improved efficiency, would facilitate proof-of-concept studies for curing HIV infection.

Full Announcement 


Image-guided Drug Delivery in Cancer (R01)

Deadline:  November 19, 2015

This Funding Opportunity Announcement (FOA) will support innovative research projects that are focused on image-guided drug delivery (IGDD), including real-time image guidance, monitoring, quantitative in vivo characterizations and validation of delivery and response. It will support research in development of integrated imaging-based platforms for multifunctional and multiplexed drug delivery systems in cancer and other diseases, quantitative imaging assays of drug delivery, and early intervention.

Full Announcement


High Throughput Screening (HTS) to Discover Chemical Probes (X01)

Deadline:  December 4, 2015

This Resource Access Opportunity is to promote and support discovery and development of new chemical probes as research tools for use by the research community to advance the understanding of biological functions and disease mechanisms. The announcement encourages partnership between assay submitters and a funded High Throughput Screening (HTS)/chemical probe discovery facility to conduct the joint research. Through this announcement, NIH wishes to stimulate research in 1) discovery and development of novel, small molecules for their potential use in studying disease treatment relevant to the missions of the participating NIH Institutes and Centers, and 2) discovery and/or validation of novel, biological targets that will inform studies of disease mechanisms. Emphasis will be placed on assays that provide new insight into important disease targets and processes.

Full Announcement


High Throughput Screening (HTS) to Discover Chemical Probes (R03)

Deadline:  December 4, 2015

This Funding Opportunity Announcement (FOA) is to promote and support discovery and development of new chemical probes as research tools for use by the research community to advance the understanding of biological functions and disease mechanisms. The FOA will encourage partnership between assay submitters and a funded High Throughput Screening (HTS)/chemical probe discovery facility to conduct the joint research. Through this FOA, NIH wishes to stimulate research in 1) discovery and development of novel, small molecules for their potential use in studying disease treatment relevant to the missions of the participating NIH Institutes and Centers, and 2) discovery and/or validation of novel, biological targets that will inform studies of disease mechanisms. Emphasis will be placed on assays that provide new insight into important disease targets and processes.

Full Announcement


AHRQ Individual Awards for Postdoctoral Fellows (F32) National Research Service Awards (NRSA)

Deadline: December 9, 2015

The purpose of this individual postdoctoral research training fellowship is to provide support to promising fellows with the potential to become productive, independent investigators in health services research, with a research interest in areas and priorities relevant to the mission of AHRQ.

Full Announcement


Mechanism for Time-Sensitive Drug Abuse Research (R21)

Deadline: December 9, 2015

This Funding Opportunity Announcement (FOA) is issued by the National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH). The FOA is intended to support pilot, feasibility or exploratory research for up to 2 years in 4 priority areas, including: 1) responses to unexpected and time-sensitive medical system issues (e.g. opportunities to understand addiction services in the evolving health care system); 2) responses to emerging drug abuse-related HIV trends and topics (e.g. rapidly evolving drug abuse-related epidemics, time-sensitive policy or environmental changes); 3) responses to unexpected and time-sensitive criminal justice opportunities (e.g. new system and/or structural level changes) that relate to drug abuse and access and provision of health care service; and 4) responses to unexpected and time-sensitive prescription drug abuse opportunities (e.g., new state or local efforts). It should be clear that the knowledge gained from the proposed study is time-sensitive and that an expedited rapid review and funding are required in order for the scientific question to be answered.

Full Announcement


Detection of Pathogen-Induced Cancer (DPIC) (R01)

Deadline:  December 11, 2015

This Funding Opportunity Announcement (FOA), issued by the National Cancer Institute (NCI), is to encourage research projects which focus on the interactions of carcinogenic pathogens with the human microbiome and the host for the detection of pathogen-induced cancer (DPIC). This FOA encourages research to assess molecular signatures associated with risk and early detection of pathogen-induced cancer and chronic inflammation associated with progression to invasive cancer.

Full Announcement


Revision Applications to U01 Awards for Research on Imaging and Biomarkers for Early Cancer Detection (U01)

Deadline:  December 11, 2015

This Funding Opportunity Announcement (FOA) invites cooperative agreement research (U01) revision applications from investigators with active NIH U01 research project awards. Revision applications are expected to focus on combined imaging and biomarker approaches to improve screening, early cancer detection and diagnosis by integrating multi modality imaging strategies and multiplexed biomarker methodologies. Studies proposed in the revision applications must correspond to additional specific aims, expanding the scope of individual, already funded parent U01 Cooperative Agreements.

Full Announcement 


Imaging and Biomarkers for Early Cancer Detection (R01)

Deadline:  December 11, 2015

This Funding Opportunity Announcement (FOA) invites research project (R01) applications that combine imaging and biomarkers. The overall objective of this FOA is to facilitate collaborative imaging and biomarker research to improve cancer screening, early cancer detection and diagnosis by integrating multi modality imaging strategies and multiplexed biomarker methodologies.

Full Announcement 


Revision Applications to R01 Awards for Research on Imaging and Biomarkers for Early Cancer Detection (R01)

Deadline:  December 11, 2015

This Funding Opportunity Announcement (FOA) invites research project grant (R01) revision applications from investigators with active NIH R01 research project grant awards to support an expansion of the scope of funded R01 project grant awards through the addition of one or more new specific aims. Revision applications are expected to focus on combined imaging and biomarker approaches to improve screening, early cancer detection and diagnosis by integrating multi modality imaging strategies and multiplexed biomarker methodologies.

Full Announcement 


Revision Applications to R01 Awards for Research on Detection of Pathogen-Induced Cancer (DPIC) (R01)

Deadline:  December 11, 2015

This Funding Opportunity Announcement (FOA) invites revision applications (formerly called "competing revisions") from investigators with active NIH R01 research grants. These revision applications are expected to focus on the interactions of carcinogenic pathogens with the human microbiome and the host for the detection of pathogen-induced cancer (DPIC). This FOA encourages research to assess molecular signatures associated with risk and early detection of pathogen-induced cancer and chronic inflammation associated with progression to invasive cancer. Studies proposed in the revision applications must correspond to additional specific aims, expanding the scope of individual, already funded projects of the parent R01 award.

Full Announcement 


Revision Applications to U01 Awards on Detection of Pathogen-Induced Cancer (DPIC) (U01)

Deadline:  December 11, 2015

This Funding Opportunity Announcement (FOA) invites cooperative agreement research (U01) revision applications (formerly called "competing revisions") from investigators with active NIH U01 research project awards. These revision applications are expected to focus on the interactions of carcinogenic pathogens with the human microbiome and the host for the detection of pathogen-induced cancer (DPIC). This FOA encourages research to assess molecular signatures associated with risk and early detection of pathogen-induced cancer and chronic inflammation associated with progression to invasive cancer. Studies proposed in the revision applications must correspond to additional specific aims, expanding the scope of individual, already funded projects of the parent U01 Cooperative Agreement.

Full Announcement


2016


NHLBI Clinical Trial Pilot Studies (R34)

Deadline: January 7, 2016

The National Heart, Lung, and Blood Institute (NHLBI) encourages applications proposing pilot studies to obtain data that is critical for the design of robust clinical trials. This Funding Opportunity Announcement (FOA) should be used to fill gaps in scientific knowledge necessary to develop a competitive full-scale clinical trial. Appropriate pilot studies might demonstrate feasibility of an intervention or an experimental design, estimate intervention parameters, or gather other data important for the design of a trial. Applicants who propose solely to write a protocol or manual of operations or to develop infrastructure for a clinical trial will not be considered appropriate for to this announcement. Applications must demonstrate that the proposed pilot studies are both necessary and sufficient to permit the design of the clinical trial. During the evaluation of applications submitted to this FOA, the review group will also consider the significance and potential public health impact of the full-scale clinical trial that would be proposed following the R34 award period. The NHLBI anticipates that the R34 award period will yield robust investigator-initiated clinical trial grant applications for the evaluation of interventions for the treatment or prevention of heart, lung, blood, or sleep disorders.

Full Announcement


Ancillary Studies of Acute Kidney Injury, Chronic Kidney Disease, and End Stage Renal Disease Accessing Information from Clinical Trials, Epidemiological Studies, and Databases (R01)

Deadline: January 7, 2016

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and the National Heart Lung and Blood Institute (NHLBI) encourage investigator-initiated research project applications for ancillary studies to ongoing or completed clinical trials, existing administrative and clinical databases and epidemiological studies of kidney disease as well as clinical trials and epidemiological studies for other diseases or populations that lend themselves to the study of acute kidney injury and chronic kidney disease. These studies may range from new analyses of existing datasets of completed studies to additional collection of data and biological specimens in ongoing investigations. The goal of these studies should be to extend our understanding of the risk factors for developing kidney disease and their associated co-morbid illnesses such as malnutrition and cardiovascular disease, factors associated with rapid decline in kidney function among persons with chronic kidney disease, and the impact of these diseases on quality of life and mental and physical functioning. Investigations of acute kidney injury, including biomarkers are also an appropriate topic for investigation. Studies ancillary to both government and non-government supported clinical trials and epidemiological studies are encouraged. Analysis of large public access databases and other databases is also encouraged.

Full Announcement


Drug Abuse Aspects of HIV/AIDS (R01)

Deadline: January 7, 2016

This Funding Opportunity Announcement (FOA) issued by the National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH), encourages Research Project Grant (R01) applications to examine the drug abuse aspects of HIV/AIDS, including research on drug-related risk behaviors, addiction and HIV disease, and drug use/HIV-related co-morbidities and consequences. Applications are needed to identify and predict changes in the epidemiology of HIV/AIDS among injection and non-injection drug users and among their sexual partners; to develop and test interventions for primary and secondary HIV prevention, including drug treatment interventions; to improve HIV testing, counseling, and treatment services for those living with HIV/AIDS; and to address basic mechanisms involved in HIV infection and AIDS pathogenesis in the context of drug abuse and addiction.

Full Announcement


Drug Abuse Aspects of HIV/AIDS (R03)

Deadline: January 7, 2016

This Funding Opportunity Announcement (FOA) issued by the National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH), encourages Small Grant Program (R03) applications to examine the drug abuse aspects of HIV/AIDS, including research on drug-related risk behaviors, addiction and HIV disease, and drug use/HIV-related co-morbidities and consequences. Applications are needed to identify and predict changes in the epidemiology of HIV/AIDS among injection and non-injection drug users and among their sexual partners; to develop and test interventions for primary and secondary HIV prevention, including drug treatment interventions; to improve HIV testing, counseling, and treatment services for those living with HIV/AIDS; and to address basic mechanisms involved in HIV infection and AIDS pathogenesis in the context of drug abuse and addiction.

Full Announcement


Drug Abuse Aspects of HIV/AIDS (R21)

Deadline: January 7, 2016

This Funding Opportunity Announcement (FOA) issued by the National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH), encourages Exploratory/Developmental Research Grant (R21) applications to examine the drug abuse aspects of HIV/AIDS, including research on drug-related risk behaviors, addiction and HIV disease, and drug use/HIV-related co-morbidities and consequences. Applications are needed to identify and predict changes in the epidemiology of HIV/AIDS among injection and non-injection drug users and among their sexual partners; to develop and test interventions for primary and secondary HIV prevention, including drug treatment interventions; to improve HIV testing, counseling, and treatment services for those living with HIV/AIDS; and to address basic mechanisms involved in HIV infection and AIDS pathogenesis in the context of drug abuse and addiction.

Funding Announcement


Cancer Center Support Grants (CCSGs) for NCI-designated Cancer Centers (P30)

Deadline: January 7, 2016

This Funding Opportunity Announcement (FOA), issued by the National Cancer Institute (NCI), National Institutes of Health (NIH), invites new, renewal, resubmission or revision applications for P30 Cancer Center Support Grants (CCSGs) for NCI-designated Cancer Centers. CCSGs support two types of cancer centers: 1) Comprehensive Cancer Centers, which demonstrate reasonable depth and breadth of research activities in each of three major areas: basic laboratory; clinical; and prevention, control and population-based research, and which have substantial transdisciplinary research that bridges these scientific areas; and 2) Cancer Centers, which are primarily focused on basic laboratory; clinical; and prevention, cancer control, and population-based research; or some combination of these components. The purpose of both types of NCI-designated Cancer Centers is to capitalize on all institutional cancer research capabilities, integrating meritorious programs in laboratory, clinical, and population research into a single transdisciplinary research enterprise across all institutional boundaries. Cancer Centers supported through this FOA are expected: to serve as major sources of discovery of the nature of cancer and of development of more effective approaches to prevention, diagnosis, and therapy; to contribute significantly to the development of shared resources that support research; to collaborate and coordinate their research efforts with other NCI-funded programs and investigators; and to disseminate research findings for the benefit of the community.

Full Announcement


HIV/AIDS, Drug Use, and Vulnerable Populations in the US (R21)

Deadline: January 7, 2016

Despite progress in HIV/AIDS treatment and prevention and reductions in HIV/morbidity and mortality, HIV/AIDS health disparities remain a challenge that must be addressed. This FOA encourages research to identify the role(s) that drug abuse plays in fueling the epidemic in vulnerable groups (racial/ethnic minorities, men who have sex with men (MSM), youth) in the United States and to develop effective interventions to prevent new infections and to improve the health and well-being of those living with HIV/AIDS. This FOA will support studies in vulnerable populations to: 1) understand the contribution of drug abuse (both injection and non-injection) to the acquisition and/or transmission of HIV; 2) study disease progression and disease outcomes; 3) develop and/or improve prevention and treatment interventions, particularly comprehensive, integrated interventions; 4) improve the availability, delivery and quality of evidence-based prevention and treatment services across a variety of settings; and 5) address organizational, structural, and/or community level factors including social, drug-using, and sexual networks associated with health disparities.

Full Announcement


Potential Effects of Metformin on Aging and Age-Related Conditions: Small-Scale Clinical Studies and Secondary Analysis of Controlled Clinical Studies (R01)

Deadline: January 7, 2016

Emerging data from clinical studies of metformin in a variety of patient populations suggest that it may have other effects, besides being an antihyperglycemic agent, which warrant further attention in translational aging research. The objective of this FOA is to support research projects (R01) that include small-scale physiologic studies in humans or secondary analyses of data and/or stored biospecimens from controlled clinical intervention studies, to increase our understanding about the clinical translational potential of metformin to delay deleterious aging changes or to extend healthy human life span. This includes identification of specific populations particularly likely to benefit, and/or to obtain information on metformins human physiologic and cellular effects that would be useful in identifying novel molecular targets.

Full Announcement


Exploratory/Developmental Bioengineering Research Grants (EBRG) [R21]

Deadline: January 7, 2016

The purpose of this FOA is to encourage Exploratory/Developmental Bioengineering Research Grants (EBRG) applications which establish the feasibility of technologies, techniques or methods that: 1) explore a unique multidisciplinary approach to a biomedical challenge; 2) are high-risk but have a considerable pay-off; and 3) develop data which can lead to significant future research. An EBRG application may propose hypothesis-driven, discovery-driven, developmental, or design-directed research and is appropriate for evaluating unproven approaches for which there is minimal or no preliminary data.

Full Announcement


Examination of Survivorship Care Planning Efficacy and Impact [R21]

Deadline: January 7, 2016

The purpose of this Funding Opportunity Announcement (FOA) is to stimulate research to evaluate the effect of care planning on cancer survivors' health and psychosocial outcomes; self-management of late effects and adherence to cancer screening and health behavior guidelines; utilization of follow-up care; organizational-level factors influencing the implementation of care planning; and associated costs. Specifically, the FOA aims to stimulate research that will: 1) develop and test metrics for evaluating the impact of survivorship care planning; 2) evaluate the impact of survivorship care planning on cancer survivors' morbidity, self-management and adherence to care recommendations, utilization of follow-up care, and on systems outcomes, such as associated costs and impact on organizations implementing care planning; and 3) identify models and processes of care that promote effective survivorship care planning. The ultimate goal of this FOA is to generate a body of science that will inform the development and delivery of interventions and best practices in follow-up care for cancer survivors.

Full Announcement


Examination of Survivorship Care Planning Efficacy and Impact [R01]

Deadline: January 7, 2016

The purpose of this Funding Opportunity Announcement (FOA) is to stimulate research to evaluate the effect of care planning on cancer survivors' health and psychosocial outcomes; self-management of late effects and adherence to cancer screening and health behavior guidelines; utilization of follow-up care; organizational-level factors influencing the implementation of care planning; and associated costs. Specifically, the FOA aims to stimulate research that will: 1) develop and test metrics for evaluating the impact of survivorship care planning; 2) evaluate the impact of survivorship care planning on cancer survivors' morbidity, self-management and adherence to care recommendations, utilization of follow-up care, and on systems outcomes, such as associated costs and impact on organizations implementing care planning; and 3) identify models and processes of care that promote effective survivorship care planning. The ultimate goal of this FOA is to generate a body of science that will inform the development and delivery of interventions and best practices in follow-up care for cancer survivors.

Full Announcement


Drug Discovery for Nervous System Disorders (R01)

Deadline: January 7, 2016

This Funding Opportunity Announcement (FOA) encourages research grant applications directed toward the discovery and preclinical testing of novel compounds for the prevention and treatment of nervous system disorders.

Full Announcement


Drug Discovery for Nervous System Disorders (R21)

Deadline: January 7, 2016

This Funding Opportunity Announcement (FOA) encourages research grant applications directed toward the discovery and preclinical testing of novel compounds for the prevention and treatment of nervous system disorders.

Full Announcement


Improved Biomaterials for Urinary and Dialysis Catheters (STTR) (R41/R42)

Deadline: January 7, 2016

The overall goal of the funding opportunity announcement (FOA) is to support research and development of biomaterials that reduce or eliminate the adherence of cells and micro-organisms and the systemic and local inflammatory response to indwelling catheters used for dialysis or urinary drainage (e.g., intravenous, intraperitoneal, or intravesicular).

Full Announcement


Improved Biomaterials for Urinary and Dialysis Catheters (SBIR) (R43/R44)

Deadline: January 7, 2016

The overall goal of the funding opportunity announcement (FOA) is to support research and development of biomaterials that reduce or eliminate the adherence of cells and micro-organisms and the systemic and local inflammatory response to indwelling catheters used for dialysis or urinary drainage (e.g., intravenous, intraperitoneal, or intravesicular).

Full Announcement


Technological Improvements to Data Collection in NIDDK Clinical Studies (STTR) (R41/R42)

Deadline: January 7, 2016

The overall goal of the Funding Opportunity Announcement (FOA) is to support research and development of devices, software, or technology that will optimize data collection for NIDDK clinical studies.

Full Announcement


Technological Improvements to Data Collection in NIDDK Clinical Studies (SBIR) (R43/R44)

Deadline: January 7, 2016

The overall goal of the Funding Opportunity Announcement (FOA) is to support research and development of devices, software, or technology that will optimize data collection for NIDDK clinical studies.

Full Announcement


Pain in Aging (R01)

Deadline: January 7, 2016

This FOA encourages Research Project Grant (R01) applications from institutions/organizations that propose to study pain from an aging perspective, including studies of older populations, studies of age differences and age-related changes in pain processes and experiences, and studies of pain treatment and management in older adults. This FOA particularly encourages studies on 1) mechanisms and predictors of pain experience in aging, 2) development and evaluation of pain assessment tools for older adults or older model organisms, and 3) development and evaluation of pain management strategies in older adults, with particular attention to the challenges associated with treating pain in patients with multiple morbidities. Studies may address a variety of approaches and outcomes including biological (i.e., genetic, molecular, neurobiological), clinical, behavioral, psychological, and social factors. Both animal models (especially aged animals) and human subjects are appropriate for this FOA.

Full Announcement


Pain in Aging (R21)

Deadline: January 7, 2016

This FOA encourages Exploratory/Developmental Research Grant (R21) applications from institutions/organizations that propose to study pain from an aging perspective, including studies of older populations, studies of age differences and age-related changes in pain processes and experiences, and studies of pain treatment and management in older adults. This FOA particularly encourages studies on 1) mechanisms and predictors of pain experience in aging, 2) development and evaluation of pain assessment tools for older adults or older model organisms, and 3) development and evaluation of pain management strategies in older adults, with particular attention to the challenges associated with treating pain in patients with multiple morbidities. Studies may address a variety of approaches and outcomes including biological (i.e., genetic, molecular, neurobiological), clinical, behavioral, psychological, and social factors. Both animal models (especially aged animals) and human subjects are appropriate for this FOA.

Full Announcement


Pain in Aging (R03)

Deadline: January 7, 2016

This FOA encourages Small Grant (R03) applications from institutions/organizations that propose to study pain from an aging perspective, including studies of older populations, studies of age differences and age-related changes in pain processes and experiences, and studies of pain treatment and management in older adults. This FOA particularly encourages studies on 1) mechanisms and predictors of pain experience in aging, 2) development and evaluation of pain assessment tools for older adults or older model organisms, and 3) development and evaluation of pain management strategies in older adults, with particular attention to the challenges associated with treating pain in patients with multiple morbidities. Studies may address a variety of approaches and outcomes including biological (i.e., genetic, molecular, neurobiological), clinical, behavioral, psychological, and social factors. Both animal models (especially aged animals) and human subjects are appropriate for this FOA.

Full Announcement


Prescription Drug Abuse (R01)

Deadline: January 7, 2016

The National Institute on Drug Abuse (NIDA) encourages applicants to develop innovative research applications on prescription drug abuse, including research to examine the factors contributing to prescription drug abuse; to characterize the adverse medical, mental health and social consequences associated with prescription drug abuse; and to develop effective prevention and service delivery approaches and behavioral and pharmacological treatments. Applications to address these issues are encouraged across a broad range of methodological approaches including basic science, clinical, epidemiological, and health services research to define the extent of the problem of prescription drug abuse, to characterize this problem in terms of classes of drugs abused and combinations of drug types, etiology of abuse, and populations most affected (including analyses by age group, race/ethnicity, gender, and psychiatric symptomatology). Studies on individual- and patient-level factors, prescriber factors, and/or health system factors are encouraged, as are studies on all classes of prescription drugs with high abuse liability, including analgesics, stimulants, sedative/hypnotics and anxiolytics. Researchers are further encouraged to study the relationship between the prescription medication, the indication for which the medication was prescribed (e.g., pain, sleep disorder, anxiety disorder, obesity), and the environmental and individual factors contributing to abuse.

Full Announcement


Prescription Drug Abuse (R21)

Deadline: January 7, 2016

The National Institute on Drug Abuse (NIDA) encourages applicants to develop innovative research applications on prescription drug abuse, including research to examine the factors contributing to prescription drug abuse; to characterize the adverse medical, mental health and social consequences associated with prescription drug abuse; and to develop effective prevention and service delivery approaches and behavioral and pharmacological treatments. Applications to address these issues are encouraged across a broad range of methodological approaches including basic science, clinical, epidemiological, and health services research to define the extent of the problem of prescription drug abuse, to characterize this problem in terms of classes of drugs abused and combinations of drug types, etiology of abuse, and populations most affected (including analyses by age group, race/ethnicity, gender, and psychiatric symptomatology). Studies on individual- and patient-level factors, prescriber factors, and/or health system factors are encouraged, as are studies on all classes of prescription drugs with high abuse liability, including analgesics, stimulants, sedative/hypnotics and anxiolytics. Researchers are further encouraged to study the relationship between the prescription medication, the indication for which the medication was prescribed (e.g., pain, sleep disorder, anxiety disorder, obesity), and the environmental and individual factors contributing to abuse.

Full Announcement


NIA Clinical Trial Planning Grant Program (R34)

Deadline: January 7, 2016

The NIA is committed to identifying effective treatments for diseases and conditions associated with aging, including disorders of neural systems and to ascertain the associated health outcomes by supporting robust, well-planned and designed, and well-executed clinical trials. This funding opportunity announcement (FOA) aims to support the planning activities needed for the successful execution of complex and multi-site clinical trials as well as the establishment of Protocol and Manual of Procedures (MOP) as recommended by the NIA Clinical Research Study Investigator's Toolbox (http://www.nia.nih.gov/research/dgcg/clinical-research-study-investigators-toolbox/startup).

Full Announcement


Calcium Oxalate Stone Diseases (R01)

Deadline: January 7, 2016

The purpose of this Funding Opportunity Announcement (FOA) is to increase investigator interest in research into oxalate metabolism, transport and homeostasis, and oxalate stone diseases. This initiative encourages basic, clinical or epidemiological studies that utilize new and innovative approaches to study the diagnosis, treatment and prevention of these disorders.

Full Announcement


NIDCR Small Research Grants for Data Analysis and Statistical Methodology Applied to Genome-wide Data (R03)

Deadline: January 7, 2016

The purpose of this FOA is to provide support for meritorious research projects that involve secondary data analyses of genome-wide data (e.g., existing data from genome-wide association studies), relevant to human dental or craniofacial conditions or traits. Development of statistical methodology appropriate for analyzing genome-wide data, relevant to human dental or craniofacial conditions or traits, may also be proposed.

Full Announcement


Advances in Polycystic Kidney Disease (R01)

Deadline: January 7, 2016

The purpose of this Funding Opportunity Announcement (FOA) is to increase investigator interest in basic and applied investigations of the etiology and pathogenesis of Polycystic Kidney Disease (PKD), in both its autosomal dominant and autosomal recessive forms. The ultimate aim is to facilitate PKD-related research studies, which will provide the basis for new therapeutic approaches.

Full Announcement


Ancillary Studies to the NIDDK Intestinal Stem Cell Consortium (R01)

Deadline: January 7, 2016

This Funding Opportunity Announcement (FOA) encourages Research Project Grant (R01) applications to conduct ancillary studies to the NIDDK Intestinal Stem Cell Consortium (ISCC). Studies will make use of consortium collaborations, techniques or resources to accelerate research into intestinal stem cells. The proposed ancillary study must be designed to advance the scientific research mission of the NIDDK by focusing on diseases and areas of interest to the Institute and commensurate with the interests and intent of the ISCC.

Full Announcement


Development and Commercialization of Technologies to Create, Characterize or Improve Animal Models of Human Disease (STTR)(R41/R42)

Deadline:  January 7, 2016

The Division of Comparative Medicine (DCM), Office of Research Infrastructure Programs (ORIP), supports Resources that create, develop, preserve and supply a variety of high-quality animal models and related biological materials to the biomedical community. DCM-supported Resources and the research community will benefit from development and commercialization of technologies that support the husbandry, characterization, improvement and use of animal models and related biological materials. This Funding Opportunity Announcement (FOA) encourages small business concerns to submit Small Business Technology Transfer (STTR) grant applications that propose innovative approaches to further develop, improve and facilitate the use of animal models and related biological materials to meet new biomedical challenges related to improvements in the health of humans and animals.

Full Announcement 


Development and Commercialization of Technologies to Create, Characterize or Improve Animal Models of Human Disease (SBIR)(R43/R44)

Deadline:  January 7, 2016

The Division of Comparative Medicine (DCM), Office of Research Infrastructure Programs (ORIP), supports Resources that create, develop, preserve and supply a variety of high-quality animal models and related biological materials to the biomedical community. DCM-supported Resources and the research community will benefit from development and commercialization of technologies that support the husbandry, characterization, improvement and use of animal models and related biological materials. This Funding Opportunity Announcement (FOA) encourages small business concerns to submit Small Business Innovation Research (SBIR) grant applications that propose innovative approaches to further develop, improve and facilitate the use of animal models and related biological materials to meet new biomedical challenges related to improvements in the health of humans and animals.

Full Announcement 


Technological Improvements to Data Collection in NIDDK Kidney and Urology Clinical Studies (SBIR) (R41/R42)

Deadline:  January 7, 2016

The overall goal of the Funding Opportunity Announcement (FOA) is to support research and development of devices, software, or technology that will optimize data collection for NIDDK clinical studies.

Full Announcement


Technological Improvements to Data Collection in NIDDK Kidney and Urology Clinical Studies (SBIR) (R43/R44)

Deadline:  January 7, 2016

The overall goal of the Funding Opportunity Announcement (FOA) is to support research and development of devices, software, or technology that will optimize data collection for NIDDK clinical studies.

Full Announcement


Solid Organ Transplantation: Older Donors and Recipients (R01)

Deadline: January 7, 2016

This Funding Opportunity Announcement (FOA) issued by the National Institute on Aging (NIA), National Institutes of Health, invites applications that propose basic, clinical, translational, epidemiological and outcomes research on solid organ transplant (SOT) in older persons. Research may focus on, but is not limited to 1) appropriate selection of older SOT donors and recipients; 2) improved management of older SOT recipients; 3) immunology and immunosuppression pertaining to older SOT patients; and 4) healthcare disparities, utilization and costs of SOT in older patients. Research supported by this initiative is expected to enhance knowledge of immunobiology in aging and transplantation, and to provide evidence-based guidance to improve access to transplantation, organ allocation and utilization, graft survival, and short- and long-term outcomes of SOT in older persons.

Full Announcement


NEI Clinical Study Planning Grant Program (R34)

Deadline: January 7, 2016

The National Eye Institute (NEI) supports large-scale clinical vision research projects, including randomized clinical trials and epidemiologic studies. At the time of submission, applications requesting support for these activities are expected to provide detailed information regarding the study rationale, design, analytic techniques, protocols and procedures, facilities and environment, organizational structure, and collaborative arrangements. This information is best conveyed in a well-documented Manual of Procedures (MOP), the development of which represents a costly and time-consuming activity. This NEI FOA is designed to facilitate activities central to the refinement of a study protocol and procedures and the development of a detailed MOP. The NEI Clinical Study Planning Grant may be used to support the development of a MOP, as well as to conduct preliminary studies to refine study procedures or document recruitment potential. This NEI FOA is applicable to both epidemiologic and clinical trial research studies.

Full Announcement


Competitive Revision Applications for Research on Complementary Approaches to Symptom Management in Military and Veteran Populations (R01)

Deadline: January 7, 2016

This Funding Opportunity Announcement (FOA) seeks competitive revision applications (formerly called competitive supplement applications). Specifically, NCCAM is encouraging competitive revision applications to augment currently active NCCAM R01 grants. NCCAM-funded researchers are encouraged to collaborate with Veteran Health Administration (VHA) or Department of Defense (DoD) clinicians or researchers to conduct research on complementary approaches for symptom management and health in military or VA populations. The research proposed should be focused on complementary approaches to pain and symptom management or improving health in U.S. military personnel, veterans and their families.

Full Announcement


Dissemination and Implementation Research in Health (R21)

Deadline: January 7, 2016

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Full Announcement


Dissemination and Implementation Research in Health (R01)

Deadline: January 7, 2016

This Funding Opportunity Announcement (FOA) encourages investigators to submit research grant applications that will identify, develop, evaluate and refine effective and efficient methods, systems, infrastructures, and strategies to disseminate and implement research-tested health behavior change interventions, evidence-based prevention, early detection, diagnostic, treatment and management, and quality of life improvement services, and data monitoring and surveillance reporting tools into public health and clinical practice settings that focus on patient outcomes.

Full Announcement


Dissemination and Implementation Research in Health (R03)

Deadline: January 7, 2016

This Funding Opportunity Announcement (FOA) encourages investigators to submit research grant applications that will identify, develop, evaluate and refine effective and efficient methods, systems, infrastructures, and strategies to disseminate and implement research-tested health behavior change interventions, evidence-based prevention, early detection, diagnostic, treatment and management, and quality of life improvement services, and data monitoring and surveillance reporting tools into public health and clinical practice settings that focus on patient outcomes.

Full Announcement


Behavioral & Integrative Treatment Development Program (R34)

Deadline: January 7, 2016

The purpose of this FOA for R34s is to encourage investigators to propose discrete well-defined projects that can be completed within three years. Projects of interest fall within the research domain of behavioral or integrated (e.g., behavioral and pharmacological) interventions targeting: (a) substance abuse (including comorbidities); (b) prevention of acquisition or transmission of HIV infection among individuals in substance abuse treatment; (c) promotion of adherence to substance abuse treatment, HIV and addiction medications; and (d) chronic pain. Specific examples include, but are not limited to studies focusing on: 1) Stage I intervention generation; 2) Stage I pilot or feasibility and both should include the development of putative moderators, mediators, and change mechanisms. (3) Stage I studies to generate or refine substance abuse treatment or adherence interventions for use in primary care; (4) Stage I research to boost effects and increase implementability of interventions with creative use of technology.

Full Announcement


Behavioral & Integrative Treatment Development Program (R01)

Deadline: January 7, 2016

The purpose of this FOA for R01 applications is to encourage behavioral intervention development research to test efficacy, conduct clinical trials, examine mechanisms of behavior change, determine dose-response, optimize combinations, and/or ascertain best sequencing of behavioral, combined, sequential, or integrated behavioral and pharmacological (1) drug abuse treatment interventions, including interventions for patients with comorbidities, in diverse settings; (2) drug abuse treatment and adherence interventions for use in primary care; (3) drug abuse treatment and adherence interventions that utilize technologies to boost effects and increase implementability; (4) interventions to prevent the acquisition or transmission of HIV infection among individuals in drug abuse treatment; (5) interventions to promote adherence to drug abuse treatment, HIV and addiction medications; and (6) interventions to treat chronic pain. Research of interest includes but is not limited to Stage II and Stage III efficacy research.

Full Announcement


Behavioral & Integrative Treatment Development Program (R03)

Deadline: January 7, 2016

The purpose of this FOA for R03s is to encourage investigators to propose discrete well-defined projects that can be completed within two years. Projects of interest fall within the research domain of behavioral or integrated (e.g., behavioral and pharmacological) interventions targeting: (a) drug abuse (including comorbidities); (b) prevention of acquisition or transmission of HIV infection among individuals in drug abuse treatment; (c) promotion of adherence to drug abuse treatment, HIV and addiction medications; and (d) chronic pain. Specific examples include, but are not limited to studies focusing on: 1) Stage I intervention generation; 2) Stage I pilot or feasibility and both should include the development of putative moderators, mediators, and change mechanisms; (3) Stage I studies to generate or refine drug abuse treatment or adherence interventions for use in primary care; (4) Stage I research to boost effects and increase implementability of interventions with creative use of technology or through other means.

Full Announcement


Accelerating the Pace of Drug Abuse Research Using Existing Data (R01)

Deadline: January 7, 2016

The purpose of this Funding Opportunity Announcement (FOA) is to invite applications proposing the innovative analysis of existing social science, behavioral, administrative, and neuroimaging data to study the etiology and epidemiology of drug using behaviors (defined as alcohol, tobacco, prescription and other drug) and related disorders, associated HIV risk behaviors, prevention of drug use and HIV, and health service utilization. This FOA is a reissue of PAR10-018, broadened to include other existing data modalities, such as neuroimaging data residing either at the collecting institution(s) or at a third-party image repository. Under this FOA, the National Institute on Drug Abuse (NIDA), National Institute on Alcohol Abuse and Alcoholism (NIAAA), the National Cancer Institute (NCI), and the Office of Behavioral and Social Sciences (OBSSR) encourage the analyses of public use and other extant community-based or clinical datasets to their full potential in order to increase our knowledge of etiology, trajectories of drug using behaviors and their consequences, risk and resilience in the development of psychopathology, strategies to guide the development, testing, implementation, and delivery of high quality, effective and efficient services for the prevention and treatment of drug abuse and HIV.

Full Announcement


Development of Highly Innovative Tools and Technology for Analysis of Single Cells (SBIR) (R43/R44)

Deadline:  January 7, 2016

This Funding Opportunity Announcement (FOA) encourages Small Business Innovation Research (SBIR) research grant applications to develop next-generation tools that distinguish heterogeneous states among cells and have commercial potential. Applications should define the current state of technology as a benchmark against which the new tool(s) will be measured. Applications should also propose proof-of-concept testing of the tool(s) in a complex biological tissue or living organism. The new tools should provide substantially increased sensitivity, selectivity, spatiotemporal resolution, scalability or non-destructive analysis of multiple global or functional measures of single cells. These novel technologies will aid in obtaining a fine-grained, integrative and dynamic view of heterogeneous cellular states/classes and will provide innovative platforms to transform research into the cellular basis of diseases.

Full Announcement


Development and Application of PET and SPECT Imaging Ligands as Biomarkers for Drug Discovery and for Pathophysiological Studies of CNS Disorders (R21)

Deadline:  January 7, 2016

This Funding Opportunity Announcement (FOA) invites research grant applications from organizations/institutions that propose the development of novel radioligands for positron emission tomography (PET) or single photon emission computed tomography (SPECT) imaging in human brain, and that incorporate pilot or clinical feasibility evaluation in pre-clinical studies, model development, or clinical studies.

Full Announcement 


NIDA Research Center of Excellence Grant Program (P50)

Deadline:  January 7, 2016

This Funding Opportunity Announcement (FOA) is to provide support for research Centers that (1) conduct drug abuse and addiction research in any area of NIDAs mission, (2) have outstanding innovative science, (3) are multidisciplinary, thematically integrated, synergistic, and (4) serve as national resource(s) to provide educational and outreach activities to drug abuse research communities, educational organizations, the general public, and policy makers in the NIDA research fields. It is expected that a Center will transform knowledge in the sciences it is studying. Incremental work should not be the focus of Center activities; rather, new and creative directions are required. The P50 Center of Excellence is expected to support the education, training, and mentoring of new investigators who would be given meaningful roles to play in the Center projects. A goal of this program is to create NIDA Centers that are national community resources for drug abuse research by sharing their findings, their data and their resources to further advance research in this field.

Full Announcement 


National Cooperative Reprogrammed Cell Research Groups (NCRCRG) to Study Mental Illness (U19)

Deadline:  January 7, 2016

The purpose of the National Cooperative Reprogrammed Cell Research Groups (NCRCRG) program is to create multidisciplinary research groups, in partnership with academia and industry, to use patient-derived reprogrammed cells to develop validated platforms for identifying novel targets and developing new therapeutics or diagnostic tools to reduce the burden of mental illness. The collaborations will be pre-competitive, meaning that they lie at the interface between basic academic research and proprietary industrial research and involve cooperation between groups that might otherwise be competitors, with a focus on optimizing tools and measures needed for successful translational research. The Funding Opportunity Announcement (FOA) encourages applications to further develop promising cellular differentiation/characterization protocols and/or disease-relevant assays using patient-derived reprogrammed cells (e.g., induced pluripotent stem cells or iPSCs, induced neuronal cells or iNCs). Critical features of these applications should be (1) a strong emphasis on developing methodology that is robust and replicable across several performance sites, and (2) cross-paradigm validation to yield predictive value for pathophysiology.

Full Announcement 


Research Grants Using the Resources from the Osteoarthritis Initiative (OAI)(R21)

Deadline:  January 7, 2016

This Funding Opportunity Announcement (FOA) encourages applications focused on the use the Osteoarthritis Initiative (OAI) database, clinical data and images. This FOA seeks to expand the use of these resources by investigators in the broader research community

Full Announcement 


Research Grants Using the Resources from the Osteoarthritis Initiative (OAI) (R01)

Deadline:  January 7, 2016

This Funding Opportunity Announcement (FOA) encourages applications for research awards that are focused on the use the Osteoarthritis Initiative (OAI) database, clinical data and images. This FOA seeks to expand the use of these resources by investigators in the broader research community.

Full Announcement 


Novel NeuroAIDS Therapeutics: Integrated Preclinical/Clinical Program (P01)

Deadline:  January 7, 2016

The National Institute of Mental Health invites research grant applications to develop innovative programs to advance therapeutics for NeuroAIDS. This Funding Opportunity Announcement (FOA) will support research programs that will advance central nervous system (CNS)-focused therapeutic approaches to: a) address HIV-associated neurocognitive disorders in HIV-infected individuals on highly active anti-retroviral therapy (HAART), b) eradicate persistent HIV-1 from the CNS during chronic infection, c) prevent establishment of HIV-1 in the brain during early infection, and d) assess the potential for CNS toxicity using HAART or candidate drugs that are currently in clinical studies to eradicate HIV-1.

Full Announcement 


Exploratory/Developmental Bioengineering Research Grants (EBRG) [R21]

Deadline: January 8, 2016

The purpose of this FOA is to encourage Exploratory/Developmental Bioengineering Research Grants (EBRG) applications which establish the feasibility of technologies, techniques or methods that: 1) explore a unique multidisciplinary approach to a biomedical challenge; 2) are high-risk but have a considerable pay-off; and 3) develop data which can lead to significant future research. An EBRG application may propose hypothesis-driven, discovery-driven, developmental, or design-directed research and is appropriate for evaluating unproven approaches for which there is minimal or no preliminary data.

Full Announcement


NIAID Clinical Trial Implementation Grant (R01)

Deadline:  January 13, 2016

This Funding Opportunity Announcement (FOA) issued by the National Institute of Allergy and Infectious Diseases (NIAID) invites applications for implementation of investigator-initiated, non-high-risk clinical trials. The trials must be hypothesis-driven, related to the research mission of the NIAID and considered a high priority by the Institute. Investigators are encouraged to visit the NIAID website for additional information about the research mission and high-priority research areas of the NIAID (http://www3.niaid.nih.gov/about/whoWeAre/planningPriorities/). Only one clinical trial may be proposed in each NIAID Clinical Trial Implementation (R01) Grant application.

Full Announcement 


NIAID Clinical Trial Planning Grant (R34)

Deadline:  January 13, 2013

This Funding Opportunity Announcement (FOA) issued by the National Institute of Allergy and Infectious Diseases (NIAID) invites applications that propose the complete planning, design, and preparation of the documentation necessary for implementation of investigator-initiated clinical trials. The trials must be hypothesis-driven, milestone-defined, related to the research mission of the NIAID and considered high priority by the Institute. Investigators are encouraged to visit the NIAID website for additional information about the research mission and high-priority research areas of the NIAID (http://www3.niaid.nih.gov/about/whoWeAre/planningPriorities/).

Full Announcement


NIAID Clinical Trial Implementation Cooperative Agreement (U01)

Deadline:  January 13, 2016

This Funding Opportunity Announcement (FOA) issued by the National Institute of Allergy and Infectious Diseases (NIAID) invites cooperative agreement applications for implementation of investigator-initiated, high-risk clinical trials and mechanistic studies associated with high-risk clinical trials. Mechanistic work in clinical trials may be of great value because it promotes the understanding of human diseases and the development of future therapeutic modalities.

Full Announcement 


NINDS Neuroscience Development for Advancing the Careers of a Diverse Research Workforce (R25)

Deadline:  January 25, 2016

The purpose of the FOA is to invite applications for mentoring and professional activities to advance the careers and neuroscience development of diverse neuroscience researchers. The goal of the NINDS Neuroscience Development for Advancing the Careers of a Diverse Research Workforce (NDACDRW) is to support mission relevant development and/or implementation of programs to: (1) increase the pool of Ph.D.-level research scientists from diverse backgrounds underrepresented in biomedical research who are neuroscience researchers- participation is limited to graduate, post-doctoral and/or junior-faculty career levels only; and (2) facilitate career advancement/transition of the participants to the next step of their neuroscience careers. NINDS support for R25 program relies equally on scientific merit and programmatic considerations. Consequently, we recommend that potential applicants contact program officials at NINDS before preparing an application. NINDS will not support projects if they do not fulfill current programmatic priorities at NINDS.

Full Announcement 


AHRQ Mentored Clinical Scientist Research Career Development Award (K08)

Deadline: February 12, 2016

This funding opportunity announcement (FOA) solicits individual Mentored Clinical Scientist Research Career Development (K08) grant applications from applicant organizations. The overall goal of AHRQ-supported career development programs is to help ensure that a diverse pool of highly trained health services researchers are available in adequate numbers and in appropriate research areas to address the mission and priorities of AHRQ.

Full Announcement


Early-Stage Pharmacological Validation of Novel Targets and Accompanying Pre-Therapeutic Leads for Diseases of Interest to the NIDDK (R01)

Deadline: March 7, 2016

The overarching goal of this Funding Opportunity Announcement (FOA) is to promote translation of basic science research into knowledge and tools that can be utilized to provide strong justification for later-phase drug discovery and development efforts in areas relevant to the National Institute of Diabetes and Digestive and Kidney Diseases. This includes obesity, diabetes and related aspects of endocrinology and metabolism, digestive diseases, liver diseases, nutrition, kidney and urological diseases, hematology, and specific aspects of cystic fibrosis. For additional information on disease areas of interest to the NIDDK, please see http://www2.niddk.nih.gov/Research/ .

Full Announcement


Mechanism for Time-Sensitive Research Opportunities in Environmental Health Sciences (R21)

Deadline:  April 1, 2016

This funding opportunity announcement (FOA) is intended to support environmental health research in which an unpredictable opportunity has arisen to collect human biosample or exposure data (e.g., following natural or made-made disasters, health care policy changes, etc). The three distinguishing features of an eligible study are: 1) the unforeseeable nature of the opportunity; 2) the clear scientific value and feasibility of the study; and 3) the need for rapid review and funding (substantially shorter than the typical NIH grant review/award cycle) in order for the scientific question to be approached and for the research design to be implemented.

Full Announcement


Effects of In Utero Alcohol Exposure on Adult Health and Disease (R21)

Deadline: May 7, 2016

This Funding Opportunity Announcement (FOA), issued by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), is intended to support novel research on how prenatal alcohol exposure may contribute to the etiology of chronic diseases and health conditions later in life. Central to this theme is the developmental origins of health and disease (DOHaD) concept which suggests that fetal adaptations in response to adverse intrauterine conditions may increase the risk for childhood and adulthood disease. The goal of this FOA is to stimulate a broad range of research to: 1) leverage existing prospective birth cohorts to define the role of maternal alcohol consumption in the DOHaD process; 2) investigate the biological, cellular, and molecular mechanisms by which prenatal alcohol exposure may impact disease outcomes later in life; and 3) identify biomarkers associated with gestational alcohol exposure that may predict adult disease susceptibility in exposed offspring. Studies supported by this FOA will provide fundamental insights into a possible fetal-basis to adult disease that is influenced by maternal alcohol use.

Full Announcement


Effects of In Utero Alcohol Exposure on Adult Health and Disease (R01)

Deadline: May 7, 2016

This Funding Opportunity Announcement (FOA), issued by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), is intended to support novel research on how prenatal alcohol exposure may contribute to the etiology of chronic diseases and health conditions later in life. Central to this theme is the developmental origins of health and disease (DOHaD) concept which suggests that fetal adaptations in response to adverse intrauterine conditions may increase the risk for childhood and adulthood disease. The goal of this FOA is to stimulate a broad range of research to: 1) leverage existing prospective birth cohorts to define the role of maternal alcohol consumption in the DOHaD process; 2) investigate the biological, cellular, and molecular mechanisms by which prenatal alcohol exposure may impact disease outcomes later in life; and 3) identify biomarkers associated with gestational alcohol exposure that may predict adult disease susceptibility in exposed offspring. Studies supported by this FOA will provide fundamental insights into a possible fetal-basis to adult disease that is influenced by maternal alcohol use.

Full Announcement


Epigenetic Inheritance and Transgenerational Effects of Alcohol (R01)

Deadline: May 7, 2016

This Funding Opportunity Announcement (FOA), issued by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), encourages Research Project Grant (R01) applications proposing to conduct mechanistic studies in humans and animal models on alcohol-induced transgenerational effects and the role of epigenetic inheritance in these effects.

Full Announcement


Epigenetic Inheritance and Transgenerational Effects of Alcohol (R21)

Deadline: May 7, 2016

This Funding Opportunity Announcement (FOA), issued by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), encourages Exploratory/Developmental Research grant (R21) applications proposing to conduct studies in humans and animal models on alcohol-induced transgenerational effects and the role of epigenetic inheritance in these effects.

Full Announcement


Secondary Dataset Analyses in Heart, Lung, and Blood Diseases and Sleep Disorders (R21)

Deadline: May 7, 2016

The purpose of this funding opportunity is to stimulate well-focused secondary analyses of existing human datasets to test innovative hypotheses concerning the epidemiology, pathophysiology, prevention or treatment of diseases/conditions relevant to the NHLBI mission. Analyzing existing datasets in novel ways provides a cost-effective method to address research questions and generate preliminary data for subsequent research proposals.

Full Announcement


Initiative to Maximize Research Education in Genomics: Courses (R25)

Deadline: May 7, 2016

This funding opportunity supports short, advanced level courses that are intended to disseminate new techniques, methods, and analyses related to the mission of the NHGRI.

Full Announcement


NIA Limited Competition: Renewals of, and Revisions to, Existing Cooperative agreement Awards (U01)

Deadline:  May 7, 2016

This FOA invites existing cooperative agreements that are described below (Part 2, Section I) to submit revision and or renewal applications. Potential applicants are strongly encouraged to contact their current program officer prior to submission to discuss the application.

Full Announcement


School Nutrition and Physical Activity Policies, Obesogenic Behaviors, and Weight Outcomes (R21)

Deadline:  May 7, 2016

This Funding Opportunity Announcement (FOA) is issued by the National Institutes of Health's Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), the National Cancer Institute (NCI), the National Heart, Lung, and Blood Institute (NHLBI), and the Office of Behavioral and Social Sciences Research (OBSSR). The FOA encourages Research Project Grant (R21) applications that propose to: (1) foster multidisciplinary research that will evaluate how policies (federal, state and school district levels) can influence school physical activity and nutrition environments, youths obesogenic behaviors (e.g., nutrition and physical activity behaviors), and weight outcomes; (2) understand how schools are implementing these policies and examine multi-level influences on adoption and implementation at various levels (e.g., federal, state, school district, and school); and (3) understand the synergistic or counteractive effect of school nutrition and physical activity polices on the home and community environment and body weight.

Full Announcement 


School Nutrition and Physical Activity Policies, Obesogenic Behaviors and Weight Outcomes (R03)

Deadline:  May 7, 2016

This Funding Opportunity Announcement (FOA) is issued by the National Institutes of Health's Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Cancer Institute (NCI), and the Office of Behavioral and Social Sciences Research (OBSSR). The FOA encourages research project grant (R03) applications that propose to: (1) foster multidisciplinary research that will evaluate how policies (federal, state and school district levels) can influence school physical activity and nutrition environments, youths obesogenic behaviors (e.g., nutrition and physical activity behaviors), and weight outcomes; (2) understand how schools are implementing these policies and examine multi-level influences on adoption and implementation at various levels (e.g., federal, state, school district, and school); and (3) understand the synergistic or counteractive effect of school nutrition and physical activity polices on the home and community environment and body weight. The R03 grant mechanism supports different types of projects including pilot and feasibility studies; secondary analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology.

Full Announcement


School Nutrition and Physical Activity Policies, Obesogenic Behaviors and Weight Outcomes (R01)

Deadline:   May 7, 2016

This Funding Opportunity Announcement (FOA) is issued by the National Institutes of Health's Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), the National Cancer Institute (NCI), the National Heart, Lung, and Blood Institute (NHLBI), and the Office of Behavioral and Social Sciences Research (OBSSR). The FOA encourages Research Project Grant (R01) applications that propose to: (1) foster multidisciplinary research that will evaluate how policies (federal, state and school district levels) can influence school physical activity and nutrition environments, youths obesogenic behaviors (e.g., nutrition and physical activity behaviors), and weight outcomes; (2) understand how schools are implementing these policies and examine multi-level influences on adoption and implementation at various levels (e.g., federal, state, school district, and school); and (3) understand the synergistic or counteractive effect of school nutrition and physical activity polices on the home and community environment and body weight.

Full Announcement


Disorders of Human Communication: Effectiveness, Outcomes and Health Services Research (R21)

Deadline:  May 7, 2016

The purpose of this Funding Opportunity Announcement (FOA) is to support effectiveness, outcomes and health services research in the NIDCD mission areas of hearing, balance, smell, taste, voice, speech and language.

Full Announcement 


Disorders of Human Communication: Effectiveness, Outcomes and Health Services Research (R01)

Deadline:  May 7, 2016

The purpose of this Funding Opportunity Announcement (FOA) is to support effectiveness, outcomes and health services research in the NIDCD mission areas of hearing, balance, smell, taste, voice, speech and language.

Full Announcement 


Obesity Policy Evaluation Research (R01)

Deadline: May 7, 2016

This Funding Opportunity Announcement (FOA) encourages Research Project Grant (R01) applications that propose to evaluate large scale policy or programs that are expected to influence obesity related behaviors (e.g., dietary intake, physical activity, or sedentary behavior) and/or weight outcomes in an effort to prevent or reduce obesity.

Full Announcement 


Mechanistic Insights from Birth Cohorts (R01)

Deadline:  May 7, 2016

This Funding Opportunity Announcement (FOA) is intended to support novel research on how prenatal exposures contribute to the etiology of chronic diseases and health conditions later in life. The goal of this FOA is to stimulate research by leveraging existing birth cohorts to address targeted mechanistic questions regarding the normal and abnormal developmental origins of organ systems and/or diseases of interest to the participating NIH Institutes and Centers.

Full Announcement


Improvement of Animal Models for Stem Cell-Based Regenerative Medicine (R24)

Deadline:  May 7, 2016

This FOA encourages Resource-Related Research Project Grant (R24) applications from institutions and organizations proposing research aimed at characterizing animal stem cells and improving existing and creating new animal models for human disease conditions. The intent of this initiative is to facilitate the use of stem cell-based therapies for regenerative medicine. The initiative focuses on the following areas: 1) comparative analysis of animal and human stem cells to provide information for selection of the most predictive and informative model systems; 2) development of new technologies for stem cell characterization and transplantation; and 3) improvement of animal disease models for stem cell-based therapeutic applications.

Full Announcement


Improvement of Animal Models for Stem Cell-Based Regenerative Medicine (R01)

Deadline:  May 7, 2016

This FOA encourages Research Project Grant (R01) applications from institutions and organizations proposing research aimed at characterizing animal stem cells and improving existing, and creating new, animal models for human disease conditions. The intent of this initiative is to facilitate the use of stem cell-based therapies for regenerative medicine. The initiative focuses on the following areas: 1) comparative analysis of animal and human stem cells to provide information for selection of the most predictive and informative model systems; 2) development of new technologies for stem cell characterization and transplantation; and 3) improvement of animal disease models for stem cell-based therapeutic applications.

Full Announcement


Improvement of Animal Models for Stem Cell-Based Regenerative Medicine (R21)

Deadline:  May 7, 2016

This FOA encourages Exploratory/Developmental Research grant (R21) applications from institutions and organizations proposing research aimed at characterizing animal stem cells and improving existing, and creating new, animal models for human disease conditions. The intent of this initiative is to facilitate the use of stem cell-based therapies for regenerative medicine. The initiative focuses on the following areas: 1) comparative analysis of animal and human stem cells to provide information for selection of the most predictive and informative model systems; 2) development of new technologies for stem cell characterization and transplantation; and 3) improvement of animal disease models for stem cell-based therapeutic applications.

Full Announcement


Mechanisms, Models, Measurement, & Management in Pain Research (R03)

Deadline:  May 7, 2016

The purpose of this Funding Opportunity Announcement (FOA) is to inform the scientific community of the pain research interests of the various Institutes and Centers (ICs) at the National Institutes of Health (NIH) and to stimulate and foster a wide range of basic, clinical, and translational studies on pain as they relate to the missions of these ICs. New advances are needed in every area of pain research, from the micro perspective of molecular sciences to the macro perspective of behavioral and social sciences. Although great strides have been made in some areas, such as the identification of neural pathways of pain, the experience of pain and the challenge of treatment have remained uniquely individual and unsolved. Furthermore, our understanding of how and why individuals transition to a chronic pain state after an acute injury is limited. Research to address these issues conducted by interdisciplinary and multidisciplinary research teams is strongly encouraged, as is research from underrepresented, minority, disabled, or women investigators.

Full Announcement


Mechanisms, Models, Measurement, & Management in Pain Research (R01)

Deadline:  May 7, 2016

The purpose of this Funding Opportunity Announcement (FOA) is to inform the scientific community of the pain research interests of the various Institutes and Centers (ICs) at the National Institutes of Health (NIH) and to stimulate and foster a wide range of basic, clinical, and translational studies on pain as they relate to the missions of these ICs. New advances are needed in every area of pain research, from the micro perspective of molecular sciences to the macro perspective of behavioral and social sciences. Although great strides have been made in some areas, such as the identification of neural pathways of pain, the experience of pain and the challenge of treatment have remained uniquely individual and unsolved. Furthermore, our understanding of how and why individuals transition to a chronic pain state after an acute injury is limited. Research to address these issues conducted by interdisciplinary and multidisciplinary research teams is strongly encouraged, as is research from underrepresented, minority, disabled, or women investigators.

Full Announcement


Mechanisms, Models, Measurement, & Management in Pain Research (R21)

Deadline:  May 7, 2016

The purpose of this Funding Opportunity Announcement (FOA) is to inform the scientific community of the pain research interests of the various Institutes and Centers (ICs) at the National Institutes of Health (NIH) and to stimulate and foster a wide range of basic, clinical, and translational studies on pain as they relate to the missions of these ICs. New advances are needed in every area of pain research, from the micro perspective of molecular sciences to the macro perspective of behavioral and social sciences. Although great strides have been made in some areas, such as the identification of neural pathways of pain, the experience of pain and the challenge of treatment have remained uniquely individual and unsolved. Furthermore, our understanding of how and why individuals transition to a chronic pain state after an acute injury is limited. Research to address these issues conducted by interdisciplinary and multidisciplinary research teams is strongly encouraged, as is research from underrepresented, minority, disabled, or women investigators.

Full Announcement


Research on Alcohol and HIV/AIDS (R03)

Deadline:  May 7, 2016

This Funding Opportunity Announcement (FOA) is intended to appeal to a broad audience of alcohol and HIV/AIDS researchers, including alcohol researchers with no prior experience in HIV/AIDS research but with a keen appreciation for the relationship between problem drinking and HIV/AIDS and a strong interest in acquiring such experience; HIV/AIDS researchers with no prior alcohol research experience who realize the importance of more intensive alcohol interventions to improving clinical outcomes among HIV-infected individuals; and those with prior research experience in the area of co-occurring HIV/AIDS and alcohol and other substance abuse. The primary objective for this announcement is to support small research projects : 1) to characterize the relative importance of reducing alcohol misuse in the prevention of acquisition and transmission of HIV in order to identify and apply appropriate alcohol and HIV interventions as public health measures; 2) to more fully understand and prevent the progression of HIV disease in the presence of continued alcohol exposure; and 3) to develop operational research frameworks for addressing the occurrence and persistence of infections in high-risk populations (e.g. minority women, young gay men, etc.), and translate findings into effective, culturally appropriate preventive and treatment interventions for these targeted populations.

Full Announcement


Research on Alcohol and HIV/AIDS (R01)

Deadline:  May 7, 2016

This Funding Opportunity Announcement (FOA) is intended to appeal to a broad audience of alcohol and HIV/AIDS researchers, including alcohol researchers with no prior experience in HIV/AIDS research but with a keen appreciation for the relationship between problem drinking and HIV/AIDS and a strong interest in acquiring such experience; HIV/AIDS researchers with no prior alcohol research experience who realize the importance of more intensive alcohol interventions to improving clinical outcomes among HIV-infected individuals; and those with prior research experience in the area of co-occurring HIV/AIDS and alcohol and other substance abuse. The primary objectives for this announcement are to increase research: 1) to characterize the relative importance of reducing alcohol misuse in the prevention of acquisition and transmission of HIV in order to identify and apply appropriate alcohol and HIV interventions as public health measures; 2) to more fully understand and prevent the progression of HIV disease in the presence of continued alcohol exposure; and 3) to develop operational research frameworks for addressing the occurrence and persistence of infections in high-risk populations (e.g. minority women, young gay men, etc.), and translate findings into effective, culturally appropriate preventive and treatment interventions for these targeted populations. Given the breadth of research objectives included in this announcement, potential applicants are encouraged to carefully review all sections of the announcement for research opportunities.

Full Announcement


Research on Alcohol and HIV/AIDS (R21)

Deadline:  May 7, 2016

This Funding Opportunity Announcement (FOA) is intended to appeal to a broad audience of alcohol and HIV/AIDS researchers, including alcohol researchers with no prior experience in HIV/AIDS research but with a keen appreciation for the relationship between problem drinking and HIV/AIDS and a strong interest in acquiring such experience; HIV/AIDS researchers with no prior alcohol research experience who realize the importance of more intensive alcohol interventions to improving clinical outcomes among HIV-infected individuals; and those with prior research experience in the area of co-occurring HIV/AIDS and alcohol and other substance abuse. The primary objectives for this announcement are to increase innovative developmental research: 1) to characterize the relative importance of reducing alcohol misuse in the prevention of acquisition and transmission of HIV in order to identify and apply appropriate alcohol and HIV interventions as public health measures; 2) to more fully understand and prevent the progression of HIV disease in the presence of continued alcohol exposure; and 3) to develop operational research frameworks for addressing the occurrence and persistence of infections in high-risk populations (e.g. minority women, young gay men, etc.), and translate findings into effective, culturally appropriate preventive and treatment interventions for these targeted populations. Given the breadth of research objectives included in this announcement, potential applicants are encouraged to carefully review all sections of the announcement for research opportunities.

Full Announcement


NINDS Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral Fellows in MD-PhD Programs (F31)

Deadline:  May 7, 2016

The purpose of this individual predoctoral research training fellowship is to provide support for promising doctoral candidates who are enrolled in combined MD-PhD programs, who will be performing dissertation research and training in scientific health-related fields relevant to the mission of the National Institute of Neurological Disorders and Stroke.

Full Announcement


Investigator Initiated Multi-Site Clinical Trials (Collaborative R01)

Deadline:  May 7, 2016

The support of multi-site clinical trials is one strategy NHLBI uses to improve the understanding of the clinical mechanisms of disease and to improve prevention, diagnosis, and treatment. The purpose of this Funding Opportunity Announcement (FOA) is to provide a vehicle for submitting grant applications for investigator-initiated multi-site randomized controlled clinical trials. The trials may address any research question related to the mission and goals of the NHLBI and may test clinical or behavioral interventions. The FOA is appropriate for applications to conduct phase II and phase III randomized clinical trials where participants are recruited from multiple sites. Large-scale pragmatic trials (such as comparative effectiveness trials) as well as trials designed to test efficacy of an intervention are appropriate. The trials may randomize at the individual (patient) level or at a group level (e.g., randomization of clinics, schools, worksites, etc.). Clinical trials involving NHLBI mission-related rare diseases that require coordination across multiple clinical sites are also suitable for submission to this FOA. In any case, the trial should propose the most efficient study design to complete the specific aims. For additional information about the mission, strategic plan, and research interests of the NHLBI, applicants are encouraged to consult the NHLBI website (http://www.nhlbi.nih.gov/about/strategicplan/index.htmThis Funding Opportunity Announcement is not intended for support of single-center studies or multicenter observational studies that are not testing an intervention. Clinical Coordination Center (CCC) and Data Coordination Center (DCC) applications are required to be submitted together when the proposed costs of the clinical trial exceed $500,000 (minus F&A for subcontracts) in any given year.

Full Announcement


Understanding and Promoting Health Literacy (R01)

Deadline:  May 7, 2016

The goal of this program announcement is to encourage methodological, intervention and dissemination research for understanding and promoting health literacy. Health literacy is defined as the degree to which individuals have the capacity to obtain, process, and understand basic health information and services needed to make appropriate health decisions (Ratzan and Parker, 2000).

Full Announcement


Understanding and Promoting Health Literacy (R03)

Deadline:  May 7, 2016

The goal of this program announcement is to encourage methodological, intervention and dissemination research for understanding and promoting health literacy. Health literacy is defined as the degree to which individuals have the capacity to obtain, process, and understand basic health information and services needed to make appropriate health decisions (Ratzan and Parker, 2000).

Full Announcement


Understanding and Promoting Health Literacy (R21)

Deadline:  May 7, 2016

The goal of this program announcement is to encourage methodological, intervention and dissemination research for understanding and promoting health literacy. Health literacy is defined as the degree to which individuals have the capacity to obtain, process, and understand basic health information and services needed to make appropriate health decisions (Ratzan and Parker, 2000).

Full Announcement


Program for Extramural/Intramural Alcohol Research Collaborations (U01)

Deadline:  May 7, 2016

The purpose of this funding opportunity is to encourage collaboration between alcohol researchers in the extramural community and those within the NIAAA intramural research program. The objective of this Funding Opportunity Announcement is to bring together the research expertise that, as a functioning collaborative unit, will address key alcohol-based research questions that would not otherwise be possible by the same individuals working towards similar goals in isolation. The goal of the research proposed by the collaborating investigators should address questions that advance the alcohol research field with respect to issues surrounding alcohol use disorders including dependence and the effects of alcohol on health. The NIH Intramural Scientist will be a tenured or tenure-track scientist from the NIAAA Intramural division, with whom the PD/PI has made prior contact for the collaborative project.

Full Announcement


Bioengineering Research Grants (BRG) (R01)

Deadline:  May 7, 2016

The purpose of this funding opportunity announcement is to encourage collaborations between the life and physical sciences that: 1) apply a multidisciplinary bioengineering approach to the solution of a biomedical problem; and 2) integrate, optimize, validate, translate or otherwise accelerate the adoption of promising tools, methods and techniques for a specific research or clinical problem in basic, translational, or clinical science and practice. An application may propose design-directed, developmental, discovery-driven, or hypothesis-driven research and is appropriate for small teams applying an integrative approach that can increase our understanding of and solve problems in biological, clinical or translational science.

Full Announcement 


Acute Kidney Injury in Older Adults (R01)

Deadline:  May 7, 2016

This Funding Opportunity Announcement (FOA) invites applications that propose basic, clinical, translational and outcomes research on acute kidney injury (AKI) in older persons. Applications may focus on the 1) epidemiology, etiology and risk factors for AKI in older adults, 2) pathophysiology of AKI in the aging kidney and its impact on chronic kidney disease (CKD) and other organ disease 3) early detection, diagnosis and monitoring of AKI, and 4) prevention, treatment and management strategies of AKI in older patients with the goal of improving short- and long-term outcomes including morbidity, mortality, progression of CKD, functional independence and quality of life. Research supported by this initiative should enhance knowledge of the increasing incidence of AKI in older persons and its consequences and provide evidence-based guidance in the diagnosis, prevention, and treatment of AKI in this expanding segment of the population. Studies in both human subjects and animal models are appropriate under this FOA as warranted by the study questions.

Full Announcement


Acute Kidney Injury in Older Adults (R03)

Deadline:  May 7 2016

This Funding Opportunity Announcement (FOA) invites applications that propose basic, clinical, translational and outcomes research on acute kidney injury (AKI) in older persons. This funding initiative supports small research projects that can be carried out in a short period of time with limited resources including pilot and feasibility studies, secondary analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology. Applications may focus on the 1) epidemiology, etiology and risk factors for AKI in older adults, 2) pathophysiology of AKI in the aging kidney and its impact on chronic kidney disease (CKD) and other organ disease 3) early detection, diagnosis and monitoring of AKI, and 4) prevention, treatment and management strategies of AKI in older patients with the goal of improving short- and long-term outcomes including morbidity, mortality, progression of CKD, functional independence and quality of life. Research supported by this initiative should enhance knowledge of the increasing incidence of AKI in older persons and its consequences and provide evidence-based guidance in the diagnosis, prevention, and treatment of AKI in this expanding segment of the population. Studies in both human subjects and animal models are appropriate under this FOA as warranted by the study questions.

Full Announcement


Acute Kidney Injury in Older Adults (R21)

Deadline:  May 7, 2016

This Funding Opportunity Announcement (FOA) invites applications that propose basic, clinical, translational and outcomes research on acute kidney injury (AKI) in older persons. The R21 mechanism is intended to encourage exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research. Applications may focus on the 1) epidemiology, etiology and risk factors for AKI in older adults, 2) pathophysiology of AKI in the aging kidney and its impact on chronic kidney disease (CKD) and other organ disease 3) early detection, diagnosis and monitoring of AKI, and 4) prevention, treatment and management strategies of AKI in older patients with the goal of improving short- and long-term outcomes including morbidity, mortality, progression of CKD, functional independence and quality of life. Research supported by this initiative should enhance knowledge of the increasing incidence of AKI in older persons and its consequences and provide evidence-based guidance in the diagnosis, prevention, and treatment of AKI in this expanding segment of the population. Studies in both human subjects and animal models are appropriate under this FOA as warranted by the study questions.

Full Announcement


Aging Research Dissertation Awards to Increase Diversity (R36)

Deadline:  May 7, 2016

The National Institute on Aging (NIA) announces this continuing initiative to provide dissertation awards to increase diversity in the scientific research workforce engaged in research on aging and aging-related health conditions within NIA's strategic priorities.

Full Announcement 


Home and Family Based Approaches for the Prevention or Management of Overweight or Obesity in Early Childhood (R01)

Deadline:  May 7, 2016

This Funding Opportunity Announcement (FOA) invites Research Project Grant (R01) applications from institutions/organizations that propose randomized clinical trials testing novel home- or family-based interventions for the prevention or management of overweight in infancy and early childhood. Tested interventions can use behavioral (including dietary and physical activity), environmental, or other relevant approaches.

Full Announcement


Home and Family Based Approaches for the Prevention or Management of Overweight or Obesity in Early Childhood (R21)

Deadline:  May 7, 2016

This Funding Opportunity Announcement (FOA) invites exploratory pilot/feasibility study and small clinical trial (R21) applications from institutions/organizations that propose to test novel home or family based interventions for the prevention or management of overweight in infancy and early childhood. Tested interventions can use behavioral (including dietary and physical activity), environmental, or other relevant approaches.

Full Announcement


Innovative Research Methods: Prevention and Management of Symptoms in Chronic Illness (R01)

Deadline:  May 7, 2016

This funding opportunity seeks to update the randomized control trial (RCT) design using novel research methods that are practical, innovative, and hold promise for producing more effective outcomes. Novel clinical research designs, applied to symptom management trials, may identify those treatment strategies that best alter the course of symptom burden in chronic illness by addressing the issues of varied treatment responses across patients, subject retention, and adherence to treatment regimens. For example, sequential multiple assignment randomization trials (SMART) design have been used successfully to develop dynamic treatment regimens for alcohol, depression and HIV infection but are not widely used in symptom management trials. The approach is pragmatic in that it mimics clinical practice by allowing a re-evaluation of treatment options based on an individuals progress towards treatment goals. The levels or inclusion of intervention components are tailored in response to individual characteristics or progress toward a treatment goal. Subjects may be randomly assigned several times to varying amounts and types of intervention components based on predetermined decision rules.

Full Announcement


Innovative Research Methods: Prevention and Management of Symptoms in Chronic Illness (R21)

Deadline:  May 7, 2016

This funding opportunity seeks to update the randomized control trial (RCT) design using novel research methods that are practical, innovative, and hold promise for producing more effective outcomes. Novel clinical research designs, applied to symptom management trials, may identify those treatment strategies that best alter the course of symptom burden in chronic illness by addressing the issues of varied treatment responses across patients, subject retention, and adherence to treatment regimens. For example, sequential multiple assignment randomization trials (SMART) design have been used successfully to develop dynamic treatment regimens for alcohol, depression and HIV infection but are not widely used in symptom management trials. The approach is pragmatic in that it mimics clinical practice by allowing a re-evaluation of treatment options based on an individuals progress towards treatment goals. The levels or inclusion of intervention components are tailored in response to individual characteristics or progress toward a treatment goal. Subjects may be randomly assigned several times to varying amounts and types of intervention components based on predetermined decision rules.

Full Announcement


Secondary Analyses of Existing Data Sets and Stored Biospecimens to Address Clinical Aging Research Questions (R01)

Deadline:  May 7, 2016

This funding opportunity announcement (FOA)) invites applications employing secondary analysis of existing data sets or stored biospecimens, to address clinically-related issues on aging changes influencing health across the life span, and/or on diseases and disabilities in older persons. This FOA will support activities addressing specific hypotheses in clinical aging research and/or to inform the design and implementation of future epidemiologic or human intervention studies, or current geriatric practice in maintenance of health, management of disease, and prevention of disability. Existing data sets may also be used to develop and test new statistical analytical approaches. Costs for archiving of data to be made publicly available may be included in the budget, as long as the archival activities are pertinent to the proposed secondary analyses.

Full Announcement


Alcohol Use Disorders: Treatment, Services, and Recovery Research (R01)

Deadline:  May 7, 2016

This Funding Opportunity Announcement (FOA) encourages grant applications from institutions/organizations that propose to supportresearch on behavioral and pharmacological treatment for alcohol use disorders; organizational, financial, and management factors that facilitate or inhibit the delivery of services for alcohol use disorders; and phenomenon of recovery from alcohol use disorders.

Full Announcement


Alcohol Use Disorders: Treatment, Services, and Recovery Research (R21)

Deadline:  May 7, 2016

This Funding Opportunity Announcement (FOA) encourages grant applications from institutions/organizations that propose to supportresearch on behavioral and pharmacological treatment for alcohol use disorders; organizational, financial, and management factors that facilitate or inhibit the delivery of services for alcohol use disorders; and phenomenon of recovery from alcohol use disorders.

Full Announcement


Alcohol Use Disorders: Treatment, Services, and Recovery Research (R03)

Deadline:  May 7, 2016

This Funding Opportunity Announcement (FOA) encourages grant applications from institutions/organizations that propose to supportresearch on behavioral and pharmacological treatment for alcohol use disorders; organizational, financial, and management factors that facilitate or inhibit the delivery of services for alcohol use disorders; and phenomenon of recovery from alcohol use disorders.

Full Announcement


Drug Abuse Dissertation Research (R36)

Deadline:  May 7, 2016

The purpose of this Funding Opportunity Announcement (FOA) is to invite applications for support of drug abuse doctoral dissertation research.

Full Announcement


Addressing Health Disparities in NIDDK Diseases (R01)

Deadline:  May 7, 2016

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health (NIH) seeks research to improve understanding of the causes of high priority diseases in the United States and to develop and test more effective interventions for reducing/eliminating health disparities. Research is encouraged in the following high priority diseases within the scientific mission areas of the NIDDK: diabetes, obesity, nutrition-related disorders, hepatitis C, gallbladder disease, H. Pylori infection, sickle cell disease, kidney diseases, urologic diseases, hematologic diseases, metabolic, gastrointestinal, hepatic, and renal complications from infection with HIV.

Full Announcement 


Reducing the Duration of Untreated Psychosis in the United States (R34)

Deadline:  May 7, 2016

Approximately 100,000 adolescents and young adults in the United States experience a first episode of psychosis (FEP) every year. The early phase of psychotic illness is widely viewed as a critical opportunity for indicated prevention, and a chance to alter the downward trajectory and poor outcomes associated with serious mental disorders such as schizophrenia. Multi-element FEP specialty care programs can produce a range of positive clinical and functional outcomes. The timing of treatment is critical; short and long-term outcomes are better when individuals begin treatment close to the onset of psychosis. Numerous studies find a substantial delay between the onset of psychotic symptoms and the initiation of treatment; in the U.S. treatment is typically delayed between one and three years, suggesting that many FEP persons are missing a critical opportunity to benefit from early intervention. Early identification, rapid referral to specialty FEP care, and engagement in phase-specific treatment are essential to shortening the duration of untreated psychosis (DUP) and pre-empting functional deterioration. The World Health Organization advocates reducing DUP to 3 months or less by addressing bottlenecks in the pathway from early psychosis identification to initiation of specialty care. Accordingly, this Funding Opportunity Announcement (FOA) will support R34 grants that (1) identify a baseline rate of DUP in community treatment systems that include evidence-based specialty care programs for FEP; (2) map referral pathways to FEP care, (3) identify gaps and bottlenecks in the referral pathway, and (4) develop and pilot test feasible strategies for substantially reducing DUP among persons with FEP.

Full Announcement 


Reducing the Duration of Untreated Psychosis in the United States (R01)

Deadline:  May 7, 2016

Approximately 100,000 adolescents and young adults in the United States experience a first episode of psychosis (FEP) every year. The early phase of psychotic illness is widely viewed as a critical opportunity for indicated prevention, and a chance to alter the downward trajectory and poor outcomes associated with serious mental disorders such as schizophrenia. Multi-element FEP specialty care programs can produce a range of positive clinical and functional outcomes. The timing of treatment is critical; short and long-term outcomes are better when individuals begin treatment close to the onset of psychosis. Numerous studies find a substantial delay between the onset of psychotic symptoms and the initiation of treatment; in the U.S. treatment is typically delayed between one and three years, suggesting that many FEP persons are missing a critical opportunity to benefit from early intervention. Early identification, rapid referral to specialty FEP care, and engagement in phase-specific treatment are essential to shortening the duration of untreated psychosis (DUP) and pre-empting functional deterioration. The World Health Organization advocates reducing DUP to 3 months or less by addressing bottlenecks in the pathway from early psychosis identification to initiation of specialty care. Accordingly, this Funding Opportunity Announcement (FOA) with set-aside funds will support R01 grants that test reproducible strategies for substantially reducing DUP among persons with FEP by removing significant bottlenecks in the pathway to specialty FEP care.

Full Announcement 


Structural Interventions, Alcohol Use, and Risk of HIV/AIDS (R01)

Deadline:  May 7, 2016

This FOA encourages R01 research grant applications from institutions/organizations that propose to investigate the effectiveness of structural interventions aimed at reducing the risk of HIV/AIDS transmission by changing the environment of alcohol use. Although a variety of structural and environmental interventions have been employed successfully to reduce other drinking-related problems, similar research extending into the realm of HIV/AIDS risk reduction is still in its developing stages.

Full Announcement 


Structural Interventions, Alcohol Use, and Risk of HIV/AIDS (R21)

Deadline:  May 7, 2016

This FOA encourages R21 research grant applications from institutions/organizations that propose to investigate the effectiveness of structural interventions aimed at reducing the risk of HIV/AIDS transmission by changing the environment of alcohol use. Although a variety of structural and environmental interventions have been employed successfully to reduce other drinking-related problems, similar research extending into the realm of HIV/AIDS risk reduction is still in its developing stages. This FOA will utilize the R21 grant mechanism and runs in parallel with a FOA of identical scientific scope that encourages applications under the R01 grant mechanism.

Full Announcement 


The Role of Extracellular RNA in Mediating the Health Effects of Alcohol (R21)

Deadline:  May 7, 2016

The purpose of this FOA is to provide support for innovative research into the role of extracellular RNA (exRNA) in the development of alcohol-related diseases and end-organ injuries. As used here, the term exRNA refers to RNA molecules circulating outside of cells, either within vesicles or associated with carrier molecules. It is anticipated that this FOA will generate data that may lead to breakthroughs in our understanding of the role of exRNA communication in the initiation, progression and maintenance of the diverse medical disorders caused by excessive, long-term alcohol consumption. In the future this knowledge may be critical in the diagnosis, treatment and management of vulnerable patient populations debilitated by the vast array of alcohol-induced pathologies and enable clinicians to improve disease outcomes and, consequently, public health. In addition, research supported by this FOA may also provide information on the mechanistic basis of the health benefits of moderate alcohol consumption.

Full Announcement 


Preclinical Research on Model Organisms to Predict Treatment Outcomes for Disorders Associated with Intellectual and Developmental Disabilities (R01)

Deadline:  May 7, 2016

This funding opportunity announcement (FOA) encourages Research Project Grant (R01) applications from institutions/ organizations addressing preclinical research in model organisms of neurodevelopmental disorders. Applications submitted to this FOA should propose to develop, validate, and/or calibrate outcome measures, surrogate markers, and biomarkers in model organisms that can inform and effectively translate to human clinical trials for individuals with intellectual and developmental disabilities (IDD). In addition, applications may propose to conduct rigorous, controlled and standardized preclinical animal trials designed for safety, toxicity, and efficacy prediction or to perform an independent validation of efficacy in animals prior to human clinical trials. The goal of this FOA is to accelerate and improve the preclinical testing of candidate treatments and therapeutic compounds in order to move promising new drug therapies into clinical trials. Potential applicants may be interested in the FOA Outcome Measures For Use In Treatment Trials of Individuals with Intellectual and Developmental Disabilities.

Full Announcement 


Outcome Measures for Use in Treatment Trials for Individuals with Intellectual and Developmental Disabilities (R01)

Deadline:  May 7, 2016

This funding opportunity announcement (FOA) encourages Research Project Grant (R01) applications from institutions/organizations that propose to develop informative outcome measures for use in clinical trials for individuals with intellectual and developmental disabilities (IDD). This FOA will address a significant need in the field, one that is especially apparent in efforts to develop pharmacological treatments for these populations. This FOA will focus ongoing clinical and translational research on a neglected area essential for therapy and pharmacological treatment development. Potential applicants also may be interested in the FOA Preclinical Research on Model Organisms to Predict Treatment Outcomes for Disorders Associated with Intellectual and Developmental Disabilities (R01).

Full Announcement


Research on Autism Spectrum Disorders (R01)

Deadline:  May 7, 2016

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Full Announcement 


Research on Autism Spectrum Disorders (R21)

Deadline:  May 7, 2016

This Funding Opportunity Announcement (FOA) encourages research grant applications to support research designed to elucidate the etiology, epidemiology, diagnosis, treatment, and optimal means of service delivery in relation to autism spectrum disorders (ASD). Basic, clinical, and applied studies are encouraged. The R21 grant mechanism is intended to encourage exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on biomedical, behavioral, or clinical research.

Full Announcement 


Research on Autism Spectrum Disorders (R03)

Deadline:  May 7, 2016

This Funding Opportunity Announcement (FOA) encourages research grant applications to support research designed to elucidate the etiology, epidemiology, diagnosis, treatment, and optimal means of service delivery in relation to autism spectrum disorders (ASD). Basic, clinical, and applied studies are encouraged. The R03 award mechanism supports different types of projects including pilot and feasibility studies; secondary analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology. The R03 is intended to support small research projects that can be carried out in a short period of time with limited resources.

Full Announcement 


Improvement of Animal Models and Development of Technologies for Stem Cell-Based Regenerative Medicine (SBIR)(R43/R44)

Deadline:  May 7, 2016

This Funding Opportunity Announcement (FOA) encourages Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) that propose to develop or improve technologies for obtaining, characterizing and testing animal and human stem cells and their derivatives as models for stem cell-based regenerative medicine using animal models. The program is intended to support projects devoted to the creation of informative animal models for regenerative medicine, which will facilitate testing the safety and therapeutic potential of animal and human stem cells and their derivatives for pre-clinical evaluation. The initiative focuses on the following areas: 1) comparative analysis of animal and human stem cells to provide information for selection of the most predictive and informative model systems; 2) development of new technologies for stem cells and their derivatives, including production, characterization and transplantation; and 3) improvement of animal disease models for stem cell-based therapeutic applications. The ultimate objective of these efforts should be to provide commercial products and technologies that can help develop future clinical therapies.

Full Announcement 


Improvement of Animal Models and Development of Technologies for Stem Cell-Based Regenerative Medicine (STTR)(R41/R42)

Deadline:  May 7, 2016

This Funding Opportunity Announcement (FOA) encourages Small Business Technology Transfer (STTR) grant applications from small business concerns (SBCs) that propose to develop or improve technologies for obtaining, characterizing and testing animal and human stem cells and their derivatives as models for stem cell-based regenerative medicine using animal models. The program is intended to support projects devoted to the creation of informative animal models for regenerative medicine, which will facilitate testing the safety and therapeutic potential of animal and human stem cells and their derivatives for pre-clinical evaluation. The initiative focuses on the following areas: 1) comparative analysis of animal and human stem cells to provide information for selection of the most predictive and informative model systems; 2) development of new technologies for stem cells and their derivatives, including production, characterization and transplantation; and 3) improvement of animal disease models for stem cell-based therapeutic applications. The ultimate objective of these efforts should be to provide commercial products and technologies that can help develop future clinical therapies.

Full Announcement 


NIDDK Program Projects (P01)

Deadline:  May 7, 2016

This Funding Opportunity Announcement (FOA) issued by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) invites submission of investigator-initiated program project applications. The proposed programs should address scientific areas relevant to the NIDDK mission including diabetes, endocrine and metabolic diseases, digestive diseases and nutrition, and kidney, urologic and hematologic diseases, as well as new approaches to prevent, treat and cure these diseases, including clinical research. A description of NIDDK scientific program areas can be found at http://www2.niddk.nih.gov/Funding/default.htm.

Full Announcement 


NIAID SBIR Phase II Clinical Trial Implementation Cooperative Agreement (U44)

Deadline:  May 13, 2016

This Funding Opportunity Announcement (FOA) invites Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) that propose to implement investigator-initiated clinical trials related to the research mission of the NIAID.

Full Announcement 


NIDCD Research Career Enhancement Award for Established Investigators (K18)

Deadline:  May 8, 2016

The purpose of the NIDCD Research Career Enhancement Award for Established Investigators (K18) program is to enable established, proven investigators to augment or redirect their research programs through the acquisition of new research skills to answer questions relevant to the hearing, balance, smell, taste, voice, speech and language sciences.

Full Announcement


Limited Competition: Initiative to Maximize Research Education in Genomics (R25): Diversity Action Plan

Deadline: September 6, 2016

This funding opportunity seeks to facilitate the training of individuals at all careers levels (the undergraduate, graduate, post baccalaureate, postdoctoral and faculty levels) from diverse backgrounds underrepresented in scientific disciplines relevant to genomics to enable them to pursue genomics research that spans all areas of interest to NHGRI later in their careers. This is a limited competition funding opportunity announcement and is limited to PD(s)/PI(s) with NHGRI applications or grants in the following areas: Centers of Excellence in Genome Science; databases, large-scale sequencing and institutional training grants. In all cases, the PD/PI of any of the previous applications/grants cited above, must be the PD/PI of the R25.

Full Announcement


Differentiation and Integration of Stem Cells (Embryonic and Induced-Pluripotent) Into Developing or Damaged Tissues (R21)

Deadline:  September 7, 2016

This Funding Opportunity Announcement (FOA) issued by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) is intended to encourage innovative and high risk/impact research in the area of stem cell biology, to be explored in model organisms. The research proposed under this program can explore approaches and concepts new to this area; development of new technologies; or initial research and development of data upon which significant future research may be built. The primary focus of the FOA is to promote in vivo studies of stem cells in animal models and in humans (if applicable) to better understand how stem cells function within developing or damaged tissues. The areas of emphasis would include systematically profiling and cataloging changes at genetic and epigenetic levels that take place in stem cells and their microenvironment.

Full Announcement


Differentiation and Integration of Stem Cells (Embryonic and Induced-Pluripotent) Into Developing or Damaged Tissues (R01)

Deadline:  September 7, 2016

The primary focus of the FOA is to promote in vivo studies of stem cells in animal models and in humans (if applicable) to better understand how stem cells function within developing or damaged tissues. The areas of emphasis would include systematically profiling and cataloging changes at genetic and epigenetic levels that take place in stem cells and their microenvironment. The purpose is to gain in-depth knowledge of the mechanisms involved in: progressive differentiation of Embryonic Stem Cells (ESCs) into embryonic lineages, progenitor cells and specialized cell types; adult stem cells/progenitor cells during tissue regeneration and wound healing; and Induced Pluripotent Stem Cells (iPSCs) at the site of injury during stem cell therapy. Understanding the basic mechanisms and application of knowledge-based approaches would allow researchers to generate iPSCs that are more closely related to the ESCs at both genetic and epigenetic levels. Furthermore, it is expected that replicating developmental mechanisms would ameliorate the safety concerns associated with incomplete differentiation and improper integration of cells in damaged or diseased tissues during stem cell therapy.

Full Announcement 


Regional and International Differences in Health and Longevity at Older Ages (R03)

Deadline:  September 7, 2016

This Funding Opportunity Announcement (FOA) encourages Small Grant (R03) applications from institutions/organizations proposing to advance knowledge on the reasons behind the divergent trends that have been observed in health and longevity at older ages, both across industrialized nations and across geographical areas in the United States. This FOA is intended to capitalize on provocative findings in the literature which have been insufficiently understood and addressed. This FOA is also intended to capitalize on NIAs investment in the development of cross-nationally comparable datasets that can be harnessed to study these research questions; these include the Health and Retirement Study (HRS), the English Longitudinal Study on Ageing (ELSA), the Survey of Health, Ageing and Retirement in Europe (SHARE), and the Human Mortality Data Base. Applications proposing secondary analysis, calibration of measures across studies, development of innovative survey measures, and linkages to administrative sources are encouraged. Applications are not restricted to projects using the NIA-supported datasets above and may propose research using any relevant data.

Full Announcement


Regional and International Differences in Health and Longevity at Older Ages (R21)

Deadline:  September 7, 2016

This Funding Opportunity Announcement (FOA) encourages Research Project Grant (R01) applications from institutions/organizations proposing to advance knowledge on the reasons behind the divergent trends that have been observed in health and longevity at older ages, both across industrialized nations and across geographical areas in the United States. This FOA is intended to capitalize on provocative findings in the literature which have been insufficiently understood and addressed. This FOA is also intended to capitalize on NIAs investment in the development of cross-nationally comparable datasets that can be harnessed to study these research questions; these include the Health and Retirement Study (HRS), the English Longitudinal Study on Ageing (ELSA), the Survey of Health, Ageing and Retirement in Europe (SHARE), and the Human Mortality Data Base. Applications proposing secondary analysis, new data collection, calibration of measures across studies, development of innovative survey measures, and linkages to administrative sources are encouraged. Applications are not restricted to projects using the NIA-supported datasets above and may propose research using any relevant data.

Full Announcement


Regional and International Differences in Health and Longevity at Older Ages (R01)

Deadline:  September 7, 2016

This Funding Opportunity Announcement (FOA) encourages Research Project Grant (R01) applications from institutions/organizations proposing to advance knowledge on the reasons behind the divergent trends that have been observed in health and longevity at older ages, both across industrialized nations and across geographical areas in the United States. This FOA is intended to capitalize on provocative findings in the literature which have been insufficiently understood and addressed. This FOA is also intended to capitalize on NIAs investment in the development of cross-nationally comparable datasets that can be harnessed to study these research questions; these include the Health and Retirement Study (HRS), the English Longitudinal Study on Ageing (ELSA), the Survey of Health, Ageing and Retirement in Europe (SHARE), and the Human Mortality Data Base. Applications proposing secondary analysis, new data collection, calibration of measures across studies, development of innovative survey measures, and linkages to administrative sources are encouraged. Applications are not restricted to projects using the NIA-supported datasets above and may propose research using any relevant data.

Full Announcement


Mechanisms of Alcohol and Nicotine Co-Addiction (R21)

Deadline:  September 7, 2016

This FOA encourages R21 applications from institutions/organizations that propose to study neurobiological and behavioral mechanisms contributing to concurrent alcohol and nicotine co-addiction.

Full Announcement 


Mechanisms of Alcohol and Nicotine Co-Addiction (R01)

Deadline:  September 7, 2016

This FOA encourages R01 applications from institutions/organizations that propose to study neurobiological and behavioral mechanisms contributing to concurrent alcohol and nicotine co-addiction.

Full Announcement 


Biomarkers for Diabetes, Digestive, Kidney and Urologic Diseases Using Biosamples from the NIDDK Repository (R01)

Deadline:  September 7, 2016

This FOA will provide support for assays (and associated data analysis) of repository-held samples for studies focused on an NIDDK-relevant disease. The review of applications to this FOA will consider both access to repository-held samples and funding for assays using the samples. These studies are expected to generate scientific discoveries on disease mechanisms, disease pathogenic processes, disease progression, or clinical responses. Projects that make good use of the associated data from the clinical trials and studies, the original intent of the clinical study and/or trial are highly encouraged. Exploratory studies and discovery research are encouraged especially when samples are not severely limited, the work is justified, and the goal is consistent with the original intent of the clinical research.

Full Announcement 


Symptom Management in HIV-Infected Individuals with Comorbid Conditions (R01)

Deadline:  September 7, 2016

This funding opportunity announcement is seeking research focused on development, adaptation, or testing interventions aimed at identifying and managing symptoms related to HIV-Associated Non-AIDS (HANA) conditions, specifically functional capacity and frailty and increasing resilience (self-care) of HIV-infected persons with HANA.

Full Announcement 


Symptom Management in HIV-Infected Individuals with Comorbid Conditions (R21)

Deadline:  September 7, 2016

This funding opportunity announcement is seeking research focused on development, adaptation, or testing interventions aimed at identifying and managing symptoms related to HIV-Associated Non-AIDS (HANA) conditions, specifically functional capacity and frailty and increasing resilience (self-care) of HIV-infected persons with HANA.
Full Announcement 


Innovative Measurement Tools for Community Engaged Research Efforts (R01)

Deadline:  September 7, 2016

This funding opportunity announcement issued by the National Institute of Nursing Research (NINR) seeks to develop innovative measurement tools for community engaged research efforts.

Full Announcement 


Innovative Measurement Tools for Community Engaged Research Efforts (R21)

Deadline:  September 7, 2016

This funding opportunity announcement issued by the National Institute of Nursing Research (NINR) seeks to develop innovative measurement tools for community engaged research efforts.

Full Announcement


Phenotyping Embryonic Lethal Knockout Mice (R01)

Deadline:  September 7, 2016

The purpose of this Funding Opportunity Announcement (FOA) is to encourage applications to phenotype embryonic lethal knockout (KO) mouse strains being generated through the International Mouse Phenotyping Consortium (IMPC) of which the NIH Knockout Mouse Phenotyping Program (KOMP2) is a member.

Full Announcement


NINDS Research Education Opportunities (R25)

Deadline:  September 7, 2016

The purpose of this funding opportunity announcement is to request applications for the initiation or continuation of nationally-available neuroscience research education programs that will significantly advance the mission of NINDS.

Full Announcement 


NIAID Resource-Related Research Projects (R24)

Deadline:  September 7, 2016

This Funding Opportunity Announcement (FOA), issued by the National Institute of Allergy and Infectious Diseases (NIAID), requests submission of investigator-initiated Resource-Related Research Projects (R24) applications. The proposed resource must provide a significant benefit to currently funded high priority projects in need of further coordination and support in the areas specified. Under rare circumstances, this mechanism may be used to support development of a new resource to the broader scientific community of the NIAID. It is anticipated that the request for resource support through the R24 activity code will occur on an infrequent basis and only in circumstances where other mechanisms of support from the NIAID are not appropriate.

Full Announcement 


Research to Characterize and Reduce Stigma to Improve Health (R21)

Deadline:  September 7, 2016

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Full Announcement 


Research to Characterize and Reduce Stigma to Improve Health (R03)

Deadline:  September 7, 2016

This Funding Opportunity Announcement (FOA) encourages research grant applications to characterize the role of stigma in health, life course development, and aging, both in the U.S. and globally, and to test interventions to prevent or reduce the impact of stigma at the individual, community, health care system, and policy levels. The goal of this FOA is to promote research addressing the health-related aspects of stigma, including the etiology and perpetuation of stigma; its impact on physical and mental health, well-being, life course development, and aging; its influence on health behaviors and on use, access to, and quality of received healthcare services; its contribution to health disparities affecting vulnerable demographic groups; and intervention strategies to reduce health-related stigma and/or the negative health and life course developmental impacts of stigma.

Full Announcement 


Resource-Related Research Projects for Development of Animal Models and Related Materials (R24)

Deadline:  September 7, 2016

This FOA encourages Resource-Related Research Project (R24) grant applications aimed at developing, characterizing or improving animal models of human diseases or improving diagnosis and control of diseases of laboratory animals. The animal models and related materials to be developed must address the research interests of two or more of the categorical NIH Institutes and Centers. In addition, projects that predominantly address the research interests of one NIH Institute or Center, but that are peripherally related to the research interests of other Institutes and Centers will not be considered appropriate for this FOA. An example of an inappropriate request is one exclusively involving an animal model of cancer.

Full Announcement


Research to Characterize and Reduce Stigma to Improve Health (R01)

Deadline:  September 7, 2016

This Funding Opportunity Announcement (FOA) encourages research grant applications to characterize the role of stigma in health, life course development, and aging, both in the U.S. and globally, and to test interventions to prevent or reduce the impact of stigma at the individual, community, health care system, and policy levels. The goal of this FOA is to promote research addressing the health-related aspects of stigma, including the etiology and perpetuation of stigma; its impact on physical and mental health, well-being, life course development, and aging; its influence on health behaviors and on use, access to, and quality of received healthcare services; its contribution to health disparities affecting vulnerable demographic groups; and intervention strategies to reduce health-related stigma and/or the negative health and life course developmental impacts of stigma.

Full Announcement 


NIAID Investigator Initiated Program Project Applications (P01)

Deadline:  September 7, 2016

This Funding Opportunity Announcement (FOA) invites submission of investigator-initiated Program Project (P01) applications. The proposed programs may address scientific areas relevant to the NIAID mission including the biology, pathogenesis, and host response to microbes, including HIV; the mechanisms of normal immune function and immune dysfunction resulting in autoimmunity, immunodeficiency, allergy, asthma, and transplant rejection; and translational research to develop vaccines, therapeutics, and diagnostics to prevent and treat infectious, immune-mediated, and allergic diseases. Each P01 application submitted to this FOA must include at least two related research projects that share a common central theme, focus, and/or overall objective.

Full Announcement 


Aging Studies in the Pulmonary System (R01)

Deadline:  September 7, 2016

The purpose of this Funding Opportunity Announcement (FOA) is to promote research to explore age-associated mechanisms in pulmonary physiology, pathology and function, and their relationship to respiratory conditions and diseases that commonly occur in older populations.

Full Announcement 


NICHD Program Project Grant (P01)

Deadline:   September 7, 2016

This funding opportunity announcement (FOA) issued by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH) invites innovative, multidisciplinary, interactive, and synergistic Program Project grant applications from institutions/organizations that propose to conduct research on reproductive, developmental, behavioral, social, and rehabilitative processes that determine the health or functioning of newborns, infants, children, adults, families, and populations. The purpose of the P01 activity code is to encourage investigation of complex problems relevant to NICHD's mission and to facilitate economy of effort, space, and equipment. Under appropriate circumstances, the collaborative research effort of a Program Project can accelerate the acquisition of knowledge more effectively than a simple aggregate of research projects without thematic integration.

Full Announcement


NIA Program Project Applications (P01)

Deadline:  September 7, 2016

The National Institute on Aging invites the submission of investigator-initiated program project (P01) applications. The applications should address scientific areas relevant to the NIA mission. Each P01 application submitted to this FOA must include at least three related research projects that share a common central theme, focus, and/overall objective and an administrative core to lead the project.

Full Announcement 


NIDA Program Project Grant Applications (P01)

Deadline:  September 7, 2016

This Funding Opportunity Announcement (FOA) announces the availability of support for collaborative research by multi-disciplinary teams which is of high priority to NIDA and leads to synergistic outcomes based on the synthesis of multiple research approaches. The NIDA Program Projects funding opportunity will support research in which the funding of three or more highly meritorious projects as a group enriches both the component projects and the overall program to offer significant scientific advantages over supporting the same projects as individual research grants (i.e., synergy). For the duration of the award, each Program must consist of a minimum of three research projects focused on issues critical to advance the mission and goals of NIDA.

Full Announcement 


Secondary Analyses of Alcohol and Chronic Disease (R21)

Deadline:  September 7, 2016

This Funding Opportunity Announcement (FOA) encourages R21 applications that propose to conduct secondary analyses of alcohol as it relates to chronic disease etiology and epidemiology. The goal of this program is to facilitate cost-effective exploratory or novel studies that break new ground or extend previous discoveries toward new directions or applications.

Full Announcement  http://www07.grants.gov/search/search.do?&mode=VIEW&oppId=237315


Secondary Analyses of Alcohol and Chronic Disease (R01)

Deadline:  September 7, 2016

This Funding Opportunity Announcement (FOA) encourages R01 applications that propose to conduct secondary analyses of alcohol as it relates to chronic disease etiology and epidemiology. The goal of this program is to facilitate innovative yet cost-effective research utilizing previously collected data.

Full Announcement


Secondary Analyses of Alcohol and Chronic Disease (R03)

Deadline:   September 7, 2016

This Funding Opportunity Announcement (FOA) encourages R03 applications that propose to conduct secondary analyses of alcohol as it relates to chronic disease etiology and epidemiology. The goal of this program is to facilitate innovative yet cost-effective research utilizing previously collected data.

Full Announcement 


Implications of New Digital Media Use for Underage Drinking, Drinking-Related Behaviors, and Prevention Research (R21)

Deadline:  September 7, 2016

This Funding Opportunity Announcement (FOA) encourages R21 research grant applications from institutions/organizations that propose to investigate whether, and how, heavy involvement in new digital media usage, particularly social media and social networking sites, may influence adolescent alcohol use and drinking patterns, as well as drinking-related problems. This FOA also encourages applications proposing to explore the ways in which new digital media may be utilized as platforms for preventive interventions aimed at underage drinking and related problems.

Full Announcement


Implications of New Digital Media Use for Underage Drinking, Drinking-Related Behaviors, and Prevention Research (R01)

Deadline:  September 7,  2016

This Funding Opportunity Announcement (FOA) encourages R01 research grant applications from institutions/organizations that propose to investigate whether, and how, heavy involvement in new digital media usage, particularly social media and social networking sites, may influence adolescent alcohol use and drinking patterns, as well as drinking-related problems.

Full Announcement 


Synergizing Omic and Symptom Science (R15)

Deadline:  September 7, 2016

This Funding Opportunity Announcement (FOA) is intended to promote integration of diverse information from molecular and biological processes with patient-reported outcomes (i.e. symptoms, functional status, health-related quality of life).

Full Announcement


Synergizing Omic and Symptom Science (R01)

Deadline:  September 7, 2016

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Full Announcement 


Grand Opportunity in Medications Development for Substance-Use Disorders (U01)

Deadline:  September 7, 2016

The purpose of this Funding Opportunity Announcement (FOA) is to accelerate the development of medication for the treatment of Substance-Use Disorders (SUDs) by encouraging research applications to support a diverse array of preclinical and/or clinical research projects.

Full Announcement 


Support of NIGMS Program Project Grants (P01)

Deadline:  September 7, 2016

This funding opportunity announcement (FOA) issued by the National Institute of General Medical Sciences encourages innovative, interactive Program Project grant applications from institutions/organizations that propose to conduct research which aims to solve a significant biological problem, important for the mission of NIGMS, through a collaborative approach involving outstanding scientists.

Full Announcement


NINDS Phase III Investigator-Initiated Efficacy Clinical Trials (U01)

Deadline:  September 7, 2016

The purpose of this Funding Opportunity Announcement (FOA) is to provide a vehicle for submitting grant applications to conduct multi-site, randomized, controlled, Phase 3 clinical trials to the National Institute of Neurological Disorders and Stroke (NINDS). The trials may address questions within the mission and research interests of the NINDS. Information about the mission and research interests of the NINDS can be found at the NINDS website (http://www.ninds.nih.gov/).

Full Announcement


AHRQ Conference Grant Program (R13)

Deadline: November 1, 2016

Purpose. The Agency for Healthcare Research and Quality (AHRQ), announces its interest in supporting conferences through the AHRQ Conference Grant Program. AHRQ seeks to support conferences that help to further its mission to improve the quality, safety, efficiency, and effectiveness of health care for all Americans. The types of conferences eligible for support include: 1) Research development – conferences where issues or challenges in the practice and delivery of health care are defined and a research agenda or strategy for studying them is developed; 2) Research design and methodology – conferences where methodological and technical issues of major importance in the field of health services research are addressed or new designs and methodologies are developed; 3) Dissemination and implementation conferences conferences where research findings and evidence-based information and tools are summarized, communicated and used by organizations and individuals that have the capability to use the information to improve the outcomes, quality, access to, and cost and utilization of health care services; and/or, 4) Research training, infrastructure and career development – conferences where faculty, trainees and students are brought together with stakeholders to develop, share or disseminate research products, experiences, curricula, syllabi, training competencies. These types of conferences are not for the training of individuals in health services research.

Full Announcement


2017


Selected Topics in Transfusion Medicine (R21)

Deadline: January 7, 2017

This Funding Opportunity Announcement (FOA) issued by the National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), encourages research grant applications from investigators who propose to study research topics in blood banking and transfusion medicine aimed at improving the safety and availability of the blood supply and the practice of transfusion medicine. Specifically, research focused on improving blood donor health, the safety and availability of blood products, and improving the practice of transfusion medicine is critical to public health. Research designed to better understand the determinants of transfusion-associated adverse events and how best to minimize transfusion risks is also important. Research is also needed to maintain an adequate blood supply by minimizing the risks associated with the donation process and developing enhanced recruitment and retention programs.

Full Announcement


Selected Topics in Transfusion Medicine (R01)

Deadline: January 7, 2017

This Funding Opportunity Announcement (FOA) issued by the National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), encourages research grant applications from investigators who propose to study research topics in blood banking and transfusion medicine aimed at improving the safety and availability of the blood supply and the practice of transfusion medicine. Specifically, research focused on improving blood donor health, the safety and availability of blood products, and improving the practice of transfusion medicine is critical to public health. Research designed to better understand the determinants of transfusion-associated adverse events and how best to minimize transfusion risks is also important. Research is also needed to maintain an adequate blood supply by minimizing the risks associated with the donation process and developing enhanced recruitment and retention programs.

Full Announcement


NIDDK Multi-Center Clinical Study Implementation Planning Cooperative Agreements (U34)

Deadline:  February 14, 2017

NIDDK supports investigator-initiated, multi-center (three or more sites) clinical studies exclusively through a two-part process that includes an implementation planning cooperative agreement (U34). The U34 is designed to: (1) permit early peer review of the rationale for the proposed clinical study; (2) permit assessment of the design and protocol of the proposed study; (3) provide support for the development of documents needed for the conduct of the study, including a manual of operations; and (4) support the development of other essential elements required for the conduct of a clinical study. Completion of the required products of a U34 is a prerequisite for submission of a multi-center clinical study cooperative agreement (U01) application, which will support the actual conduct of the study. Consultation with NIDDK staff is strongly encouraged prior to the submission of the U34 application.

Full Announcement 


Advancing Medical Device Postmarket Surveillance Infrastructure and Epidemiologic Methodologies through Multi-stakeholder Partnership (U01)

Deadline:  April 30, 2017

1) To support implementation of the National Medical Device Postmarket Surveillance System through sustainable multi-stakeholder partnership 2) To develop new epidemiologic methodologies or to apply existing methodologies in new ways to provide a comprehensive understanding of medical device performance and clinical outcomes associated with device use in real-world use settings;3) To develop new systems of data collection and/or analysis to permit prospective active medical device postmarket risk identification , periodic systematic updates of comprehensive evidence syntheses, visual analytics, and other efforts to broadly apply complex methodology to diverse data sources that facilitates postmarket surveillance;4) To develop methodological approaches and/or systems that facilitate the use of postmarket information for regulatory decision making throughout the entire device lifecycle ; and 5) To support the development of and access to high quality data sources that can be used in comprehensive postmarket evaluation of medical device performance and associated outcomes.

Full Announcement


Enhancing post-market surveillance through developing registries for medical device epidemiology (U01)

Deadline:  April 30, 2017

To address identified gaps in the current postmarket surveillance system by developing new methodologies for registry data collection and linkage, or by adapting known methodologies to medical devices, and (2) To develop novel methodology that allows for use of the registry data collection infrastructure to serve multiple purposes including postmarket surveillance, device tracking through Unique Device Identifiers (UDI), prospective embedded studies, quality improvement, and other uses, and(3) To develop registries and consortia in key medical device areas to implement new registry methodologies that strategically broaden the scope of the US and international postmarket surveillance system.

Full Announcement 


2018


Occupational Safety and Health Research (R01)

Deadline:  March 5, 2018

The purpose of this grant program is to develop an understanding of the risks and conditions associated with occupational diseases and injuries, to explore methods for reducing risks and for preventing or minimizing exposure to hazardous conditions in the workplace, and to translate significant scientific findings into prevention practices and products that will effectively reduce work-related illnesses and injuries.

Full Announcement

 

 

 

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